GPBAR1 Produits
(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
Catégories
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
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Catégories GPBAR1 en vedette
GPBAR1 Anticorps
High quality antibodies with extensive validation data.
GPBAR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
GPBAR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GPBAR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN2857020
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, IHC (p)
Validations
- (2)
N° du produit
ABIN1049401
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF
Validations
N° du produit
ABIN7189041
Quantité
100 μg
Fiche technique
Fiche technique
GPBAR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966916
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6973446
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956015
Quantité
96 tests
Fiche technique
Fiche technique
GPBAR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355520
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Mammalian Cells
Validations
N° du produit
ABIN7538251
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3124225
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GPBAR1
: "Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness." dans: Biochimica et biophysica acta. Bioenergetics, Vol. 1859, Issue 9, pp. 958-974, (2018) (PubMed).: "Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation." dans: Archives of pharmacal research, Vol. 37, Issue 9, pp. 1193-200, (2014) (PubMed).
: "Spergularia marina induces glucagon-like peptide-1 secretion in NCI-H716 cells through bile acid receptor activation." dans: Journal of medicinal food, Vol. 17, Issue 11, pp. 1197-203, (2014) (PubMed).
: "TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease." dans: Immunology, Vol. 139, Issue 1, pp. 19-29, (2013) (PubMed).
: "Plasma bile acids are associated with energy expenditure and thyroid function in humans." dans: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 2, pp. 535-42, (2012) (PubMed).
: "Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice." dans: British journal of pharmacology, Vol. 168, Issue 1, pp. 225-37, (2012) (PubMed).
: "The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice." dans: Gastroenterology, Vol. 144, Issue 1, pp. 145-54, (2012) (PubMed).
: "The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis." dans: PLoS ONE, Vol. 6, Issue 10, pp. e25637, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à GPBAR1
G protein-coupled bile acid receptor 1 (GPBAR1), G protein-coupled bile acid receptor 1 (Gpbar1), G protein-coupled bile acid receptor 1 S homeolog (gpbar1.S), BG37, GPBAR1, Gpbar1, GPCR, GPCR19, GPR131, M-BAR, MGC84403, TGR5, Tgr5Protein level used designations for GPBAR1
- G-protein coupled bile acid receptor 1
- G-protein coupled bile acid receptor BG37
- G-protein coupled receptor GPCR19
- hBG37
- hGPCR19
- membrane bile acid receptor
- membrane-type receptor for bile acids
- G protein-coupled receptor TGR5
- G protein-coupled receptor
- M-BAR
- G protein-coupled bile acid receptor 1
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