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GPX4 Produits

(Glutathione Peroxidase 4 (GPX4))
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists\; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008].

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Catégories GPX4 en vedette

GPX4 Anticorps

High quality antibodies with extensive validation data.

GPX4 Kits ELISA

Reliable ELISA kits for a wide range of species.

GPX4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GPX4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (1)
  • (8)
N° du produit ABIN3015730
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
N° du produit ABIN7438652
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7439558
Quantité 100 μL
Fiche technique Fiche technique

GPX4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975523
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975657
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956199
Quantité 96 tests
Fiche technique Fiche technique

GPX4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123131
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7403591
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7404995
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GPX4

Wang, Zheng, Zhang, Zhao, Wang, Wang, Shang, Barasch, Qiu: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." dans: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).

Agbor, Demma, Mrsny, Castillo, Boll, McCormick: "The oxido-reductase enzyme glutathione peroxidase 4 (GPX4) governs Salmonella Typhimurium-induced neutrophil transepithelial migration." dans: Cellular microbiology, Vol. 16, Issue 9, pp. 1339-53, (2014) (PubMed).

Papp, Lu, Bolderson, Boucher, Singh, Holmgren, Khanna: "SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress." dans: Antioxidants & redox signaling, Vol. 12, Issue 7, pp. 797-808, (2010) (PubMed).

Schoenmakers, Agostini, Mitchell, Schoenmakers, Papp, Rajanayagam, Padidela, Ceron-Gutierrez, Doffinger, Prevosto, Luan, Montano, Lu, Castanet, Clemons, Groeneveld, Castets, Karbaschi, Aitken, Dixon et al.: "Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. ..." dans: The Journal of clinical investigation, Vol. 120, Issue 12, pp. 4220-35, (2010) (PubMed).

Blackinton, Kumaran, van der Brug, Ahmad, Olson, Galter, Lees, Bandopadhyay, Cookson: "Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease." dans: Neuroscience letters, Vol. 452, Issue 1, pp. 8-11, (2009) (PubMed).

Su, Novoselov, Sun, Moustafa, Zhou, Oko, Hatfield, Gladyshev: "Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation." dans: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 26491-8, (2005) (PubMed).

Nakagawa: "Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor." dans: Biological & pharmaceutical bulletin, Vol. 27, Issue 7, pp. 956-60, (2004) (PubMed).

Takebe, Yarimizu, Saito, Hayashi, Nakamura, Yodoi, Nagasawa, Takahashi: "A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P." dans: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 41254-8, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à GPX4

glutathione peroxidase 4 (GPX4), glutathione peroxidase 4 (Gpx4), glutathione peroxidase 4a (gpx4a), 1700027O09Rik, ATGPX4, cb563, cb691, F11L15.5, glutathione peroxidase 4, GP-GPx4, GPx-4, gpx-4, GSHPx-4, MCSP, mtPHGPx, PHGPx, Phgpx, PHGPxa, sb:cb563, snGPx, snGpx, snPHGPx, wu:fb82e03, zgc:92253

Protein level used designations for GPX4

  • phospholipid hydroperoxidase
  • phospholipid hydroperoxide glutathione peroxidase, mitochondrial
  • sperm nucleus glutathione peroxidase
  • GSHPx-4
  • phospholipid hydroperoxide glutathione peroxidase, nuclear
  • glutathione peroxidase 4
  • GPx-4
  • sperm nuclei glutathione peroxidase
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • phospholipid hydroperoxide glutathione peroxidase
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