GRIA2 Produits
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Catégories
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG\; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008].
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Catégories GRIA2 en vedette
GRIA2 Anticorps
High quality antibodies with extensive validation data.
GRIA2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GRIA2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GRIA2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (2)
- (5)
N° du produit
ABIN969524
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, ELISA, FACS
Validations
- (5)
N° du produit
ABIN5611163
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (5)
N° du produit
ABIN3031067
Quantité
100 μg
Fiche technique
Fiche technique
GRIA2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956147
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956148
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1570148
Quantité
96 tests
Fiche technique
Fiche technique
GRIA2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407175
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407172
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7424659
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GRIA2
: "Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10." dans: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 95, (2022) (PubMed).: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).
: "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition." dans: Molecular neurobiology, Vol. 55, Issue 1, pp. 763-775, (2018) (PubMed).
: "Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis." dans: Scientific reports, Vol. 8, Issue 1, pp. 12856, (2018) (PubMed).
: "The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat." dans: Behavioural brain research, Vol. 332, pp. 99-109, (2017) (PubMed).
: "Cell-free methods to produce structurally intact mammalian membrane proteins." dans: Scientific reports, Vol. 6, pp. 30442, (2016) (PubMed).
: "Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development." dans: Scientific reports, Vol. 6, pp. 35456, (2016) (PubMed).
: "Disrupting GluA2-GAPDH Interaction Affects Axon and Dendrite Development." dans: Scientific reports, Vol. 6, pp. 30458, (2016) (PubMed).
: "Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo." dans: Brain structure & function, Vol. 220, Issue 1, pp. 47-58, (2015) (PubMed).
: "TRPC3 channels critically regulate hippocampal excitability and contextual fear memory." dans: Behavioural brain research, Vol. 281, pp. 69-77, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à GRIA2
glutamate ionotropic receptor AMPA type subunit 2 (GRIA2), glutamate receptor, ionotropic, AMPA 2 (GRIA2), glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2), glutamate ionotropic receptor AMPA type subunit 2 (Gria2), glutamate receptor, ionotropic, AMPA 2a (gria2a), glutamate receptor, ionotropic, AMPA 2 S homeolog (gria2.S), GluA2, GluR-2, Glur-2, GluR-B, gluR-B, GluR-K2, GLUR2, Glur2, GluR2, glur2, glur2a, GLURB, gria2.1, HBGR2, zfGRIA2[a]Protein level used designations for GRIA2
- AMPA-selective glutamate receptor 2
- gluR-2
- gluR-B
- glutamate receptor 2
- Glutamate receptor 2
- gluR-K2
- glutamate receptor ionotropic, AMPA 2
- AMPA selective glutamate receptor
- glutamate receptor B
- glutamate receptor, ionotropic, AMPA 2.1
- AMPA glutamate receptor 2
- AMPA receptor GluR2/B
- glutamate receptor AMPA 2
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