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GRID2 Produits

(Glutamate Receptor, Ionotropic, delta 2 (GRID2))
Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq, Jul 2008].

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Catégories GRID2 en vedette

GRID2 Anticorps

High quality antibodies with extensive validation data.

GRID2 Kits ELISA

Reliable ELISA kits for a wide range of species.

GRID2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GRID2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IF, ELISA, ICC, IHC
Validations
  • (3)
N° du produit ABIN6257247
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN561131
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ELISA
Validations
  • (1)
N° du produit ABIN7184958
Quantité 100 μg
Fiche technique Fiche technique

GRID2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956153
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503169
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503171
Quantité 96 tests
Fiche technique Fiche technique

GRID2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355734
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GRID2

Landsend, Amiry-Moghaddam, Matsubara, Bergersen, Usami, Wenthold, Ottersen: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).

Zuo, De Jager, Takahashi, Jiang, Linden, Heintz: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." dans: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).

Hirano, Kasono, Araki, Mishina: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." dans: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).

Kashiwabuchi, Ikeda, Araki, Hirano, Shibuki, Takayama, Inoue, Kutsuwada, Yagi, Kang: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." dans: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).

Araki, Meguro, Kushiya, Takayama, Inoue, Mishina: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." dans: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à GRID2

glutamate receptor, ionotropic, delta 2 (grid2), glutamate receptor ionotropic, delta-2 (LOC704787), glutamate ionotropic receptor delta type subunit 2 (GRID2), glutamate receptor, ionotropic, delta 2 (Grid2), glutamate ionotropic receptor delta type subunit 2 (Grid2), glutamate receptor ionotropic, delta-2 (LOC536367), B230104L07Rik, cpr, GluD2, glurd2, GluRdelta2, GRID2, ho, Lc, Lc, MMS10-AC, Ms10ac, nmf408, si:rp71-1l7.1, tpr

Protein level used designations for GRID2

  • gluR delta-2 subunit
  • glutamate receptor delta-2 subunit
  • glutamate receptor ionotropic, delta-2
  • glutamate receptor, ionotropic, delta 2
  • glutamate receptor delta-2 subunit-like
  • GluR-delta-2
  • creeper
  • hotfoot
  • lurcher
  • minisatellite 10ac detected by probe MMS10
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