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GRIK2 Produits

(Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Catégories

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008].

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Catégories GRIK2 en vedette

GRIK2 Anticorps

High quality antibodies with extensive validation data.

GRIK2 Kits ELISA

Reliable ELISA kits for a wide range of species.

GRIK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GRIK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (5)
N° du produit ABIN7267415
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (3)
N° du produit ABIN5611208
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN3022675
Quantité 100 μL
Fiche technique Fiche technique

GRIK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN776955
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN774999
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative
Validations
N° du produit ABIN778939
Quantité 96 tests
Fiche technique Fiche technique

GRIK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355738
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418479
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2722000
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GRIK2

Kindt, Sheets: "Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish." dans: Frontiers in cell and developmental biology, Vol. 6, pp. 114, (2018) (PubMed).

Funk, Janech, Dillon, Bissler, Siroky, Bell: "Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid." dans: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 6, pp. 1187-97, (2014) (PubMed).

Gut, Beske, Hubbard, Lyman, Hamilton, McNutt: "Novel application of stem cell-derived neurons to evaluate the time- and dose-dependent progression of excitotoxic injury." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64423, (2013) (PubMed).

Motazacker, Rost, Hucho, Garshasbi, Kahrizi, Ullmann, Abedini, Nieh, Amini, Goswami, Tzschach, Jensen, Schmitz, Ropers, Najmabadi, Kuss: "A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation." dans: American journal of human genetics, Vol. 81, Issue 4, pp. 792-8, (2007) (PubMed).

Pinheiro, Mulle: "Kainate receptors." dans: Cell and tissue research, Vol. 326, Issue 2, pp. 457-82, (2006) (PubMed).

Delorme, Krebs, Chabane, Roy, Millet, Mouren-Simeoni, Maier, Bourgeron, Leboyer: "Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder." dans: Neuroreport, Vol. 15, Issue 4, pp. 699-702, (2004) (PubMed).

Tanaka: "Functions of glutamate transporters in the brain." dans: Neuroscience research, Vol. 37, Issue 1, pp. 15-9, (2000) (PubMed).

Paschen, Blackstone, Huganir, Ross: "Human GluR6 kainate receptor (GRIK2): molecular cloning, expression, polymorphism, and chromosomal assignment." dans: Genomics, Vol. 20, Issue 3, pp. 435-40, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à GRIK2

glutamate ionotropic receptor kainate type subunit 2 (GRIK2), glutamate receptor, ionotropic, kainate 2 L homeolog (grik2.L), glutamate receptor, ionotropic, kainate 2 (grik2), glutamate ionotropic receptor kainate type subunit 2 (Grik2), glutamate receptor, ionotropic, kainate 2 (beta 2) (Grik2), AW124492, eaa4, EAA4, glr6, GLR6, GluK2, gluk6, GLUK6, Glur-6, glur6, GluR6, GLUR6, Glur6, Glurbeta2, grik2, GRIK2, grik2-A, GRIK5, mrt6, MRT6

Protein level used designations for GRIK2

  • glutamate receptor 6
  • glutamate receptor, ionotropic kainate 2
  • glutamate receptor, ionotropic, kainate 5
  • bA487F5.1
  • excitatory amino acid receptor 4
  • gluR-6
  • glutamate receptor form A
  • glutamate receptor form B
  • glutamate receptor form C
  • glutamate receptor form D
  • glutamate receptor form E
  • glutamate receptor ionotropic, kainate 2
  • gluR beta-2
  • glutamate receptor beta-2
  • glutamate receptor, ionotropic, kainate 2
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