GRK2 Produits
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
Catégories
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008].
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Catégories GRK2 en vedette
GRK2 Anticorps
High quality antibodies with extensive validation data.
GRK2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GRK2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GRK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), IF, ICC, FACS, IP
Validations
- (6)
N° du produit
ABIN2855125
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (6)
N° du produit
ABIN3022346
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, ICC
Validations
- (2)
- (4)
N° du produit
ABIN969178
Quantité
100 μL
Fiche technique
Fiche technique
GRK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964661
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964660
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964659
Quantité
96 tests
Fiche technique
Fiche technique
GRK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344492
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5508944
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
N° du produit
ABIN7317491
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GRK2
: "Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study." dans: Scientific reports, Vol. 8, Issue 1, pp. 12731, (2018) (PubMed).: "GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail." dans: Biochemistry, Vol. 48, Issue 20, pp. 4285-93, (2009) (PubMed).
: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).
: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." dans: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).
: "Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure." dans: European heart journal, Vol. 26, Issue 17, pp. 1752-8, (2005) (PubMed).
: "The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site." dans: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8052-7, (2003) (PubMed).
: "Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo." dans: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30219-26, (2003) (PubMed).
: "The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated ..." dans: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 18658-63, (2003) (PubMed).
: "Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase." dans: World journal of gastroenterology : WJG, Vol. 9, Issue 4, pp. 800-3, (2003) (PubMed).
: "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." dans: Anesthesiology, Vol. 98, Issue 2, pp. 343-8, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à GRK2
beta-adrenergic receptor kinase 1 (Tsp_00497), G protein-coupled receptor kinase 2 (grk2), G protein-coupled receptor kinase 2 (Grk2), G protein-coupled receptor kinase 2 (GRK2), Adrbk-1, Bark-1, BARK1, BETA-ARK1, betaARK1, GRK-2, GRK2, Grk2Protein level used designations for GRK2
- beta-adrenergic receptor kinase 1
- adrenergic, beta, receptor kinase 1
- G-protein-coupled receptor kinase 2
- beta ARK
- beta ARK1
- beta-AR kinase-1
- beta-ARK-1
- beta-adrenergic receptor kinase-1
- G-protein coupled receptor kinase 2
- adrenergic receptor kinase, beta 1
- beta-adrenergic receptor kinase 1 beta ARK1
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