GRM2 Produits
(Glutamate Receptor, Metabotropic 2 (GRM2))
Catégories
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories GRM2 en vedette
GRM2 Anticorps
High quality antibodies with extensive validation data.
GRM2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GRM2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GRM2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC, ICC, FACS, Neut
Validations
- (4)
N° du produit
ABIN5611158
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Bat, Cow, Dog, Hamster, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p), ICC
Validations
- (3)
N° du produit
ABIN1048929
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Rabbit
Application
IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN213522
Quantité
50 μg
Fiche technique
Fiche technique
GRM2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1743299
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1774204
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1744518
Quantité
96 tests
Fiche technique
Fiche technique
GRM2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7491675
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355778
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN1330185
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GRM2
: "Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 1, pp. 103-13, (2009) (PubMed).: "Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis." dans: Journal of neuropathology and experimental neurology, Vol. 63, Issue 8, pp. 831-40, (2004) (PubMed).
: "The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region." dans: Brain research, Vol. 1022, Issue 1-2, pp. 12-8, (2004) (PubMed).
: "Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 40, pp. 8752-61, (2004) (PubMed).
: "Control of kinetic properties of GluR2 flop AMPA-type channels: impact of R/G nuclear editing." dans: The European journal of neuroscience, Vol. 15, Issue 1, pp. 51-62, (2002) (PubMed).
: "Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus." dans: Neuropharmacology, Vol. 42, Issue 3, pp. 297-305, (2002) (PubMed).
: "Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses." dans: Nature, Vol. 410, Issue 6828, pp. 588-92, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à GRM2
glutamate metabotropic receptor 2 (GRM2), glutamate receptor, metabotropic 2 (Grm2), glutamate metabotropic receptor 2 (Grm2), 4930441L02Rik, GLUR2, GPRC1B, Gprc1b, mGlu2, MGLUR2, mGluR2, mGluR7Protein level used designations for GRM2
- glutamate metabotropic receptor 2
- glutamate receptor homolog
- metabotropic glutamate receptor 2
- G protein coupled receptor, family C, group 1, member B
- G protein-coupled receptor, family C, group 1, member B
- mGluR2
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