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GRM7 Produits

(Glutamate Receptor, Metabotropic 7 (GRM7))
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].

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Catégories GRM7 en vedette

GRM7 Anticorps

High quality antibodies with extensive validation data.

GRM7 Kits ELISA

Reliable ELISA kits for a wide range of species.

GRM7 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GRM7 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN5611160
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Horse, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN1048941
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN1048942
Quantité 50 μg
Fiche technique Fiche technique

GRM7 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381316
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1743305
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1774210
Quantité 96 tests
Fiche technique Fiche technique

GRM7 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7491677
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355787
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355786
Quantité 25 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GRM7

Fujikawa, Petralia, Fitzgerald, Wang, Millis, Morgado-Díaz, Kitamura, Kachar: "Localization of kainate receptors in inner and outer hair cell synapses." dans: Hearing research, Vol. 314, pp. 20-32, (2014) (PubMed).

Friedman, Van Laer, Huentelman, Sheth, Van Eyken, Corneveaux, Tembe, Halperin, Thorburn, Thys, Bonneux, Fransen, Huyghe, Pyykkö, Cremers, Kremer, Dhooge, Stephens, Orzan, Pfister, Bille, Parving et al.: "GRM7 variants confer susceptibility to age-related hearing impairment. ..." dans: Human molecular genetics, Vol. 18, Issue 4, pp. 785-96, (2009) (PubMed).

Vadasz, Saito, Gyetvai, Oros, Szakall, Kovacs, Prasad, Toth: "Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking." dans: Genomics, Vol. 90, Issue 6, pp. 690-702, (2007) (PubMed).

Schulz, Stohr, Weber: "Characterization of three novel isoforms of the metabotrobic glutamate receptor 7 (GRM7)." dans: Neuroscience letters, Vol. 326, Issue 1, pp. 37-40, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à GRM7

glutamate metabotropic receptor 7 (GRM7), glutamate receptor, metabotropic 7 (Grm7), glutamate metabotropic receptor 7 (Grm7), 6330570A01Rik, BB176677, C030018L03, E130018M02Rik, GLUR7, Gpr1g, GPRC1G, Gprc1g, MGLU7, MGLUR7, mGluR7

Protein level used designations for GRM7

  • metabotropic glutamate receptor 7
  • mGluR7
  • G protein-coupled receptor GRM7
  • G protein-coupled receptor, family C, group 1, member G
  • mGlu7a receptor
  • metabotropic glutamate receptor mGluR7
  • metabotropic glutamate receptor subtype 7b
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