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GRM8 Produits

(Glutamate Receptor, Metabotropic 8 (GRM8))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories GRM8 en vedette

GRM8 Anticorps

High quality antibodies with extensive validation data.

GRM8 Kits ELISA

Reliable ELISA kits for a wide range of species.

GRM8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GRM8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
N° du produit ABIN5611162
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7181343
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Bat, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep
Application IHC, IHC (p), ICC
Validations
  • (3)
N° du produit ABIN1048944
Quantité 50 μg
Fiche technique Fiche technique

GRM8 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381317
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1743306
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1774211
Quantité 96 tests
Fiche technique Fiche technique

GRM8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355789
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
N° du produit ABIN1330189
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Mammalian Cells
Validations
N° du produit ABIN7538306
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GRM8

Downey, Lozza, Petrò, Diodato, Foglia, Bottazzoli, Brusa, Asquini, Reggiani, Grilli: "Ecdysone-based system for controlled inducible expression of metabotropic glutamate receptor subtypes 2, 5, and 8." dans: Journal of biomolecular screening, Vol. 10, Issue 8, pp. 841-8, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à GRM8

glutamate metabotropic receptor 8 (GRM8), metabotropic glutamate receptor 8 (MGLUR8), metabotropic glutamate receptor 8 (LOAG_14062), glutamate receptor, metabotropic 8 (Grm8), glutamate metabotropic receptor 8 (Grm8), A230002O04, GLUR8, Glur8, GPRC1H, Gprc1h, GRM8, mGlu8, mGlur, mGluR8, MGLUR8, Mglur8, mGluR8b

Protein level used designations for GRM8

  • metabotropic glutamate receptor 8
  • metabotropic type glutamate receptor 8
  • glutamate receptor, metabotropic 8
  • G protein coupled receptor, family C, group 1, member H
  • G protein-coupled receptor, family C, group 1, member H
  • G protein-coupled receptor family C group 1 member H
  • metabotropic glutamate receptor subtype 8b
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