GSTa2 Produits
(Glutathione S-Transferase alpha 2 (GSTa2))
Catégories
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].
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Catégories GSTa2 en vedette
GSTa2 Anticorps
High quality antibodies with extensive validation data.
GSTa2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GSTa2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GSTa2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7434407
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
N° du produit
ABIN516223
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (3)
N° du produit
ABIN653362
Quantité
400 μL
Fiche technique
Fiche technique
GSTa2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967114
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956215
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Validations
N° du produit
ABIN1135014
Quantité
96 tests
Fiche technique
Fiche technique
GSTa2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306061
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7395404
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7416280
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GSTa2
: "Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions." dans: Blood advances, Vol. 1, Issue 18, pp. 1440-1451, (2018) (PubMed).: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." dans: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).
: "Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases." dans: Chemical research in toxicology, Vol. 27, Issue 12, pp. 2071-81, (2014) (PubMed).
: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." dans: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à GSTa2
glutathione S-transferase alpha 2 (GSTA2), glutathione S-transferase alpha 2 (Gsta2), glutathione S-transferase (GSTA2), glutathione S-transferase, alpha 2 (Yc2) (Gsta2), GST2, Gst2-2, GSTA1, Gsta1, GSTA2-2, Gstc-2, Gstc2, GTA2, GTH2Protein level used designations for GSTa2
- GST class-alpha member 1
- GST class-alpha member 2
- glutathione S-transferase A1
- glutathione S-transferase A2
- glutathione S-transferase alpha 1
- glutathione S-transferase alpha-1
- glutathione S-transferase alpha-2
- GST HA subunit 2
- GST-gamma
- S-(hydroxyalkyl)glutathione lyase A2
- glutathione S-alkyltransferase A2
- glutathione S-aralkyltransferase A2
- glutathione S-aryltransferase A2
- liver GST2
- GST 1-1
- GST 1a-1a
- GST A1-1
- GST B
- GST Ya1
- Glutathione-S-transferase alpha type (Yc?)
- glutathione S-transferase Ya subunit
- glutathione S-transferase Ya-1
- glutathione-S-transferase, alpha type2
- ligandin
- glutathione S-transferase alpha class A2
- glutathione S-transferase GT41A
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