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GZMA Produits

(Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Catégories

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008].

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Catégories GZMA en vedette

GZMA Anticorps

High quality antibodies with extensive validation data.

GZMA Kits ELISA

Reliable ELISA kits for a wide range of species.

GZMA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GZMA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7440233
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IP, FACS, ICC
Validations
  • (2)
N° du produit ABIN7505978
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN6141551
Quantité 100 μL
Fiche technique Fiche technique

GZMA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6956296
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956297
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999395
Quantité 96 tests
Fiche technique Fiche technique

GZMA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123196
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306259
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306257
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GZMA

Spacek, Musilova, Andrys, Soucek, Burckova, Pavlicek, Pliskova, Bolehovska, Kacerovsky: "Extracellular granzyme A in amniotic fluid is elevated in the presence of sterile intra-amniotic inflammation in preterm prelabor rupture of membranes." dans: The journal of maternal-fetal & neonatal medicine, pp. 1-10, (2020) (PubMed).

Tang, Zha, Guo, Shi, Xu: "CXCR5+CD8+ T cells present elevated capacity in mediating cytotoxicity toward autologous tumor cells through interleukin 10 in diffuse large B-cell lymphoma." dans: International immunopharmacology, Vol. 50, pp. 146-151, (2018) (PubMed).

Ma, Huang, Zhang, Wang, Chen: "Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity." dans: International immunopharmacology, Vol. 50, pp. 139-145, (2018) (PubMed).

Qiu, Hu, Gao, Chen, Chen, Yuan, Huang, Xu, Yang: "Interleukin 10 enhanced CD8+ T cell activity and reduced CD8+ T cell apoptosis in patients with diffuse large B cell lymphoma." dans: Experimental cell research, Vol. 360, Issue 2, pp. 146-152, (2017) (PubMed).

Kamata, Kimura, Matsuda, Tengara, Kamo, Umehara, Iizumi, Kawasaki, Suga, Ogawa, Tominaga, Takamori: "Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis." dans: Journal of dermatological science, Vol. 84, Issue 3, pp. 266-271, (2016) (PubMed).

Kurioka, Ussher, Cosgrove, Clough, Fergusson, Smith, Kang, Walker, Hansen, Willberg, Klenerman: "MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets." dans: Mucosal immunology, Vol. 8, Issue 2, pp. 429-40, (2015) (PubMed).

Hildebrand, Bode, Rieß, Cerny, Waldhuber, Römmler, Strack, Korten, Orth, Miethke, Heeg, Kubatzky: "Granzyme A produces bioactive IL-1? through a nonapoptotic inflammasome-independent pathway." dans: Cell reports, Vol. 9, Issue 3, pp. 910-7, (2014) (PubMed).

Herth, Witzens-Harig, Beckhove, Hose, Meissner, Neuber, Engelhardt, Haas, Neben, Ho, Klein, Goldschmidt, Hundemer: "Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma." dans: Experimental hematology, Vol. 41, Issue 3, pp. 231-40, (2013) (PubMed).

Kreft, Verbraak, Wierenga-Wolf, van Meurs, Oostra, Laman, Hintzen: "The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 4, pp. 1874-83, (2012) (PubMed).

Meade, Wilson, Holmes, de Wynter, Brett, Straszynski, Ballard, Trapani, McDermott, Cook: "Proteolytic activation of the cytotoxic phenotype during human NK cell development." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 803-13, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à GZMA

granzyme A (gzmA), granzyme A (GZMA), Granzyme A (graa), granzyme A (Gzma), granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA), AW494114, Ctla-3, Ctla3, CTLA3, gzmA, GZMA, Hf, HFSP, SE1, TSP-1, TSP1

Protein level used designations for GZMA

  • granzyme A
  • Granzyme A
  • BLT esterase
  • H factor
  • Hanukah factor
  • autocrine thymic lymphoma granzyme-like serine protease
  • fragmentin-1
  • serine esterase 1
  • t cell-specific serine protease 1
  • CTL tryptase
  • Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)
  • HF
  • cytotoxic T-lymphocyte proteinase 1
  • h factor
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