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HAND1 Produits

(Heart and Neural Crest Derivatives Expressed 1 (HAND1))
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008].

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Catégories HAND1 en vedette

HAND1 Anticorps

High quality antibodies with extensive validation data.

HAND1 Kits ELISA

Reliable ELISA kits for a wide range of species.

HAND1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HAND1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7443566
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
  • (3)
N° du produit ABIN7248206
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7154845
Quantité 100 μL
Fiche technique Fiche technique

HAND1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883165
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1136128
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1136130
Quantité 96 tests
Fiche technique Fiche technique

HAND1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306339
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2129581
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418560
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HAND1

Lu, Du, Shan, Wang, Ma, Dong: "Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture." dans: Biochemical and biophysical research communications, Vol. 478, Issue 4, pp. 1726-31, (2016) (PubMed).

Zhang, Chen, Ye, Wang, Wang, Yuan, Lin, Wu, Zhang, Lin: "Wnt signaling promotes hindgut fate commitment through regulating multi-lineage genes during hESC differentiation." dans: Cellular signalling, Vol. 29, pp. 12-22, (2016) (PubMed).

Kobayashi, Yoshida, Tarui, Hirata, Nagai, Kasahara, Naruse, Ito, Sano, Oh et al.: "Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left ..." dans: PLoS ONE, Vol. 9, Issue 7, pp. e102796, (2014) (PubMed).

Friese, Altshuler, Zhang, Miramontes-Gonzalez, Hightower, Jirout, Salem, Gayen, Mahapatra, Biswas, Cale, Vaingankar, Kim, Courel, Taupenot, Ziegler, Schork, Pravenec, Mahata, Schmid-Schönbein, OConnor: "MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension." dans: Human molecular genetics, Vol. 22, Issue 18, pp. 3624-40, (2013) (PubMed).

Reichman, Kalathur, Lambard, Aït-Ali, Yang, Lardenois, Ripp, Poch, Zack, Sahel, Léveillard: "The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina." dans: Human molecular genetics, Vol. 19, Issue 2, pp. 250-61, (2009) (PubMed).

Lexer, Welch, Durphy, Rieseberg: "Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species." dans: Molecular ecology, Vol. 12, Issue 5, pp. 1225-35, (2003) (PubMed).

Firulli, Howard, McDaid, McIlreavey, Dionne, Centonze, Cserjesi, Virshup, Firulli: "PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation." dans: Molecular cell, Vol. 12, Issue 5, pp. 1225-37, (2003) (PubMed).

Dai, Cserjesi: "The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer." dans: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12604-12, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à HAND1

cathepsin G (CTSG), heart and neural crest derivatives expressed 1 (HAND1), heart and neural crest derivatives expressed 1 (Hand1), heart and neural crest derivatives expressed 1 L homeolog (hand1.L), heart and neural crest derivatives expressed 1 (hand1), bHLHa27, CATG, CG, eHand, eHAND, EHAND, Ehand1, hand-1, HAND1, Hand1, hand1-A, Hxt, HXT, hxt, Th1, Thing1, thing1

Protein level used designations for HAND1

  • class A basic helix-loop-helix protein 27
  • extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1
  • heart- and neural crest derivatives-expressed protein 1
  • heart and neural crest derivatives expressed transcript 1
  • heart and neural crest derivatives-expressed protein 1
  • eHAND
  • heart and neural crest derivatives expressed 1
  • basic helix-loop-helix transcription factor HAND1
  • eHAND basic helix-loop-helix transcription factor
  • Heart- and neural crest derivatives-expressed protein 1
  • helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast
  • thing-1
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