HAP1 Produits
(Huntingtin Associated Protein 1 (HAP1))
Catégories
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories HAP1 en vedette
HAP1 Anticorps
High quality antibodies with extensive validation data.
HAP1 Kits ELISA
Reliable ELISA kits for a wide range of species.
HAP1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HAP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
WB, IF
Validations
- (5)
- (4)
N° du produit
ABIN968461
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN334416
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, ICC
Validations
- (3)
N° du produit
ABIN5013715
Quantité
100 μL
Fiche technique
Fiche technique
HAP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956609
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1570237
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5655203
Quantité
96 tests
Fiche technique
Fiche technique
HAP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7409197
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7416700
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417678
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HAP1
: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." dans: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).
: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." dans: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).
: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." dans: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).
: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." dans: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).
: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." dans: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).
: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." dans: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).
: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." dans: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à HAP1
huntingtin associated protein 1 (HAP1), huntingtin-associated protein 1 (Hap1), HAP-1, HAP1-A, HAP1-B, HAP2, hHLP1, HIP5, HLPProtein level used designations for HAP1
- HAP-1
- huntingtin-associated protein 2
- neuroan 1
- huntingtin-associated protein 1 (neuroan 1)
Vous êtes ici:
