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HAX1 Produits

(HCLS1 Associated Protein X-1 (HAX1))
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories HAX1 en vedette

HAX1 Anticorps

High quality antibodies with extensive validation data.

HAX1 Kits ELISA

Reliable ELISA kits for a wide range of species.

HAX1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HAX1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (5)
N° du produit ABIN2855251
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IP
Validations
  • (1)
  • (4)
N° du produit ABIN968199
Quantité 150 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7154840
Quantité 100 μg
Fiche technique Fiche technique

HAX1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1136117
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1136116
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1136118
Quantité 96 tests
Fiche technique Fiche technique

HAX1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306379
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306381
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN1098543
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HAX1

Gomathinayagam, Muralidharan, Ha, Varadarajalu, Dhanasekaran: "Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration." dans: Genes & cancer, Vol. 5, Issue 3-4, pp. 84-99, (2014) (PubMed).

Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." dans: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).

Suzuki, Demoliere, Kitamura, Takeshita, Deuschle, Watanabe: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à HAX1

HCLS1 associated protein X-1 (HAX1), HCLS1 associated protein X-1 (hax1), HCLS1 associated protein X-1 (Hax1), HCLS1 associated X-1 (Hax1), HAX-1, HAX1, hax1, HCLSBP1, HS1BP1, Hs1bp1, HSP1BP-1, mHAX-1s, SCN3, SIG-111, Silg111

Protein level used designations for HAX1

  • HCLS1 associated protein X-1
  • HCLS1-associated protein X-1
  • HAX-1
  • HCLS1 (and PKD2) associated protein
  • HS1 binding protein
  • HS1-associating protein X-1
  • HS1-binding protein 1
  • HSP1BP-1
  • HS1-associated protein X-1
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