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H13 Produits

(Histocompatibility 13 (H13))

Catégories

The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories H13 en vedette

H13 Anticorps

High quality antibodies with extensive validation data.

H13 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

H13 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
N° du produit ABIN7159822
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
  • (2)
N° du produit ABIN1387572
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat, Xenopus laevis
Application WB
Validations
  • (1)
N° du produit ABIN6746312
Quantité 100 μL
Fiche technique Fiche technique

H13 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306780
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3116824
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3129341
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits H13

Makowski, Wang, Pomerantz: "A protease-independent function for SPPL3 in NFAT activation." dans: Molecular and cellular biology, Vol. 35, Issue 2, pp. 451-67, (2014) (PubMed).

Nyborg, Kornilova, Jansen, Ladd, Wolfe, Golde: "Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor." dans: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15153-60, (2004) (PubMed).

Friedmann, Lemberg, Weihofen, Dev, Dengler, Rovelli, Martoglio: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." dans: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).

Urny, Hermans-Borgmeyer, Gercken, Schaller: "Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development." dans: Gene expression patterns : GEP, Vol. 3, Issue 5, pp. 685-91, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à H13

histocompatibility minor 13 (HM13), histocompatibility (minor) 13 (hm13), histocompatibility (minor) 13 L homeolog (hm13.L), histocompatibility 13 (H13), histocompatibility minor 13 (Hm13), 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, AV020344, cb228, dJ324O17.1, H-13, H13, h13, Hm13, IMP1, IMPAS, IMPAS-1, MGC68919, MSTP086, PSENL3, PSL3, SPP, Spp, SPPL1, wu:fc11a06, zgc:56660, zgc:86862

Protein level used designations for H13

  • IMP-1
  • hIMP1
  • intramembrane protease 1
  • minor histocompatibility antigen 13
  • minor histocompatibility antigen H13
  • presenilin-like protein 3
  • signal peptide peptidase beta
  • signal peptide peptidase like 1
  • histocompatibility 13
  • signal peptide peptidase
  • intramembrane aspartyl protease
  • histocompatibility (minor) 13
  • presenilin-like aspartyl protease
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