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HBEGF Produits

(Heparin-Binding EGF-Like Growth Factor (HBEGF))
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

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Catégories HBEGF en vedette

HBEGF Anticorps

High quality antibodies with extensive validation data.

HBEGF Kits ELISA

Reliable ELISA kits for a wide range of species.

HBEGF Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HBEGF recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN701050
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7433663
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP, ICC, IF
Validations
  • (4)
  • (4)
N° du produit ABIN2451994
Quantité 50 μg
Fiche technique Fiche technique

HBEGF recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956482
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6956483
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956484
Quantité 96 tests
Fiche technique Fiche technique

HBEGF recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123301
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7092863
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7092865
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HBEGF

Lee, Kim: "Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF." dans: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).

Wang, Zhang, Li, Mao, Sun, Chen, Zhang, Bartsch, Shu, Lei: "ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway." dans: Biomedicine & pharmacotherapy, Vol. 97, pp. 1066-1077, (2018) (PubMed).

Nawaz, Aminuddin, Kado, Takikawa, Yamamoto, Tsuneyama, Igarashi, Ikutani, Nishida, Nagai, Takatsu, Imura, Sasahara, Okazaki, Ueki, Okamura, Tokuyama, Ando, Matsumoto, Mori, Nakagawa, Kobayashi, Saeki et al.: "CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. ..." dans: Nature communications, Vol. 8, Issue 1, pp. 286, (2018) (PubMed).

Lai, Li, Chen, Pan, Wen, Mai, Yuan, Lv, Lv, Cen, Yi, Wen, Li, Wu, Wu, Cao: "Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial-mesenchymal transition." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 9, pp. 1159-1169, (2018) (PubMed).

Lim, Yoo, Kim, Hur, Lee, Hur, Lee, Lee, Park, Lee, Chang, Kim, Kang, Hong, Kim, Kim, Yoon, Nam, Yang, Kim, Cho, Won: "GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands." dans: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 251-63, (2016) (PubMed).

Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." dans: Journal of neurochemistry, (2015) (PubMed).

Fujita, Kasai, Omachi, Sakaguchi, Shinohara: "A novel method for assessing bladder-related pain reveals the involvement of nerve growth factor in pain associated with cyclophosphamide-induced chronic cystitis in mice." dans: European journal of pain (London, England), Vol. 20, Issue 1, pp. 79-91, (2015) (PubMed).

Mandl, Drechsler, Jansen, Neideck, Noels, Faussner, Soehnlein, Weber, Döring: "Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation." dans: PLoS ONE, Vol. 10, Issue 8, pp. e0134176, (2015) (PubMed).

David, Sahay, Mege, Descotes, Leblanc, Ribeiro, Clézardin, Peyruchaud: "Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers." dans: PLoS ONE, Vol. 9, Issue 5, pp. e97771, (2015) (PubMed).

Palazuelos, Crawford, Klingener, Sun, Karelis, Raines, Aguirre: "TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 36, pp. 11884-96, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à HBEGF

heparin-binding EGF-like growth factor b (hbegfb), heparin binding EGF like growth factor (HBEGF), Heparin-binding EGF-like growth factor (hbegf), heparin-binding EGF-like growth factor a (hbegfa), heparin-binding EGF-like growth factor (Hbegf), AW047313, DTR, Dtr, DTS, Dts, DTSF, GFHB, Hb-egf, HB-EGF, hbegf, HBEGF, HEGFL, Hegfl, zgc:165443, zgc:175091

Protein level used designations for HBEGF

  • proheparin-binding EGF-like growth factor
  • heparin-binding EGF-like growth factor
  • Heparin-binding EGF-like growth factor
  • diphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
  • heparin-binding epidermal growth factor
  • Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor)
  • heparin binding epidermal growth factor-like growth factor
  • heparin-binding epidermal -growth - like growth factor
  • heparin-binding epidermal -growth factor
  • diphtheria toxin receptor
  • heparin-binding epidermal growth factor-like growth factor
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