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HCLS1 Produits

(Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Catégories

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories HCLS1 en vedette

HCLS1 Anticorps

High quality antibodies with extensive validation data.

HCLS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HCLS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), PLA, RNAi
Validations
  • (7)
N° du produit ABIN516371
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (9)
N° du produit ABIN2777503
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
N° du produit ABIN516375
Quantité 100 μg
Fiche technique Fiche technique

HCLS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1136285
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1136284
Quantité 96 tests
Fiche technique Fiche technique

HCLS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306429
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306431
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN4371214
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HCLS1

Mukherjee, Kim, Mooren, Shahan, Cohan, Cooper: "Role of cortactin homolog HS1 in transendothelial migration of natural killer cells." dans: PLoS ONE, Vol. 10, Issue 2, pp. e0118153, (2015) (PubMed).

Lettau, Kabelitz, Janssen: "SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells." dans: European journal of immunology, Vol. 45, Issue 2, pp. 551-61, (2015) (PubMed).

Kan, Wen, Pasquier, Jankowski, Chang, Richards, Kavallaris, MacKenzie: "Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization." dans: Oncogene, Vol. 31, Issue 46, pp. 4815-27, (2012) (PubMed).

Ruzzene, Penzo, Pinna: "Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells." dans: The Biochemical journal, Vol. 364, Issue Pt 1, pp. 41-7, (2002) (PubMed).

Takemoto, Furuta, Li, Strong-Sparks, Hashimoto: "LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck." dans: The EMBO journal, Vol. 14, Issue 14, pp. 3403-14, (1995) (PubMed).

Fukuda, Kitamura, Taniuchi, Maekawa, Benhamou, Sarthou, Watanabe: "Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 16, pp. 7302-6, (1995) (PubMed).

Yamanashi, Okada, Semba, Yamori, Umemori, Tsunasawa, Toyoshima, Kitamura, Watanabe, Yamamoto: "Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3631-5, (1993) (PubMed).

Synonymes et noms alternatifs relatifs à HCLS1

hematopoietic cell-specific Lyn substrate 1 (HCLS1), hematopoietic cell specific Lyn substrate 1 (Hcls1), hematopoietic lineage cell-specific protein-like (LOC100223649), hematopoietic cell-specific Lyn substrate 1 (hcls1), hematopoietic cell-specific Lyn substrate 1 (Hcls1), AW213261, CTTNL, HCLS1, hcls1, HS1, si:dkey-9a20.6, wu:fk96b08, zgc:154014

Protein level used designations for HCLS1

  • hematopoietic lineage cell-specific protein
  • lckBP1
  • p75
  • hematopoietic cell-specific LYN substrate 1
  • hematopoietic cell-specific Lyn substrate 1
  • hematopoietic lineage cell-specific protein-like
  • Hematopoietic lineage cell-specific protein
  • fk96b08
  • uncharacterized protein LOC563056
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