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HCN4 Produits

(Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008].

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Catégories HCN4 en vedette

HCN4 Anticorps

High quality antibodies with extensive validation data.

HCN4 Kits ELISA

Reliable ELISA kits for a wide range of species.

HCN4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HCN4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IF, ICC, FACS, AA
Validations
  • (4)
N° du produit ABIN361779
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IF, ICC, FACS, AA
Validations
  • (4)
N° du produit ABIN2482538
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IF, ICC, FACS, AA
Validations
  • (4)
N° du produit ABIN2482537
Quantité 100 μg
Fiche technique Fiche technique

HCN4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967499
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956642
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883177
Quantité 96 tests
Fiche technique Fiche technique

HCN4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123394
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306433
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3119376
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HCN4

Stradleigh, Ishida: "Fixation strategies for retinal immunohistochemistry." dans: Progress in retinal and eye research, Vol. 48, pp. 181-202, (2015) (PubMed).

Li, Hong, Zhang, Zhou, Ji, Li, Hu, Li, Sun, Zhang, Xin, Yusufuaji, Xiong, Tang: "Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 20, pp. 2292-7, (2014) (PubMed).

Mesirca, Alig, Torrente, Müller, Marger, Rollin, Marquilly, Vincent, Dubel, Bidaud, Fernandez, Seniuk, Engeland, Singh, Miquerol, Ehmke, Eschenhagen, Nargeot, Wickman, Isbrandt, Mangoni: "Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation." dans: Nature communications, Vol. 5, pp. 4664, (2014) (PubMed).

Nam, Lubczyk, Bhakta, Zang, Fernandez-Perez, McAnally, Bassel-Duby, Olson, Munshi: "Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors." dans: Development (Cambridge, England), Vol. 141, Issue 22, pp. 4267-78, (2014) (PubMed).

Hughes, Boyle, Kinnon, Bilsland, Quayle, Callister, Graham: "HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus." dans: Neuroscience, Vol. 237, pp. 7-18, (2013) (PubMed).

Abbas, Hamade, Yang, Nawy, Smith, Pettit: "Directional summation in non-direction selective retinal ganglion cells." dans: PLoS computational biology, Vol. 9, Issue 3, pp. e1002969, (2013) (PubMed).

Al Madhoun, Voronova, Ryan, Zakariyah, McIntire, Gibson, Shelton, Ruel, Skerjanc: "Testosterone enhances cardiomyogenesis in stem cells and recruits the androgen receptor to the MEF2C and HCN4 genes." dans: Journal of molecular and cellular cardiology, Vol. 60, pp. 164-71, (2013) (PubMed).

Stoenica, Wilkars, Battefeld, Stadler, Bender, Strauss: "HCN1 subunits contribute to the kinetics of I(h) in neonatal cortical plate neurons." dans: Developmental neurobiology, Vol. 73, Issue 10, pp. 785-97, (2013) (PubMed).

Stillitano, Lonardo, Giunti, Del Lungo, Coppini, Spinelli, Sartiani, Poggesi, Mugelli, Cerbai: "Chronic atrial fibrillation alters the functional properties of If in the human atrium." dans: Journal of cardiovascular electrophysiology, Vol. 24, Issue 12, pp. 1391-400, (2013) (PubMed).

Viney, Lasztoczi, Katona, Crump, Tukker, Klausberger, Somogyi: "Network state-dependent inhibition of identified hippocampal CA3 axo-axonic cells in vivo." dans: Nature neuroscience, Vol. 16, Issue 12, pp. 1802-11, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4 (HCN4), hyperpolarization activated cyclic nucleotide gated potassium channel 4 (hcn4), hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (Hcn4), hyperpolarization-activated, cyclic nucleotide-gated K+ 4 (Hcn4), Bcng3, HAC4, Hcn3, SSS2

Protein level used designations for HCN4

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • hyperpolarization activated cyclic nucleotide-gated cation channel 4
  • potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 4
  • HAC-4
  • hyperpolarization activated cation channel
  • hyperpolarization-activated cation channel 4
  • BCNG-3
  • brain cyclic nucleotide-gated channel 3
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 3
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