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HDAC2 Produits

(Histone Deacetylase 2 (HDAC2))

Catégories

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].

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Catégories HDAC2 en vedette

HDAC2 Anticorps

High quality antibodies with extensive validation data.

HDAC2 Kits ELISA

Reliable ELISA kits for a wide range of species.

HDAC2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HDAC2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (6)
N° du produit ABIN6242378
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
N° du produit ABIN7267708
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (1)
  • (4)
N° du produit ABIN653718
Quantité 400 μL
Fiche technique Fiche technique

HDAC2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN5526695
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962266
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967435
Quantité 96 tests
Fiche technique Fiche technique

HDAC2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123344
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Hi-5 Cells
Validations
  • (1)
N° du produit ABIN667944
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412992
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HDAC2

Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." dans: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Du, Tang, Yuan: "Suppression of HDAC2 by sodium butyrate alleviates apoptosis of kidney cells in db/db mice and HG‑induced NRK‑52E cells." dans: International journal of molecular medicine, Vol. 45, Issue 1, pp. 210-222, (2020) (PubMed).

Tang, Zhou, Xiang, Wu, Zhang, Wang, Liu, Zhang, Peng, Huang, Cai, Bai, Bai, Zhu, Gu, Xiong, Ye, Li, Liu, Wang: "The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer." dans: Nature communications, Vol. 10, Issue 1, pp. 663, (2019) (PubMed).

Wu, Li, Qin, Cheng, Hao, Jin, Zhu: "Jinwei Tang modulates HDAC2 expression in a rat model of COPD." dans: Experimental and therapeutic medicine, Vol. 15, Issue 3, pp. 2604-2610, (2018) (PubMed).

Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." dans: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." dans: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

Guo, Bai, Zhao, Zhou, Shen, Yun, Zhang, Zhu, Wang: "Acetylation of 53BP1 dictates the DNA double strand break repair pathway." dans: Nucleic acids research, Vol. 46, Issue 2, pp. 689-703, (2018) (PubMed).

Wei, Lu, Ma, Yu, Zhang, Xiong, Wang, Zhang, Fang, Wang: "Synergistic activity of imatinib and AR-42 against chronic myeloid leukemia cells mainly through HDAC1 inhibition." dans: Life sciences, Vol. 211, pp. 224-237, (2018) (PubMed).

Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." dans: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).

Sirchia, Faversani, Rovina, Russo, Paganini, Savi, Augello, Rosso, Del Gobbo, Tabano, Bosari, Miozzo: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." dans: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à HDAC2

histone deacetylase 2 (HDAC2), histone deacetylase 2 (Hdac2), histone deacetylase 2 S homeolog (hdac2.S), histone deacetylase 2 (HDA2), D10Wsu179e, HD2, HISTONE DEACETYLASE, histone deacetylase 2, mRPD3, RPD3, T1N24.9, T1N24_9, YAF1, Yy1bp

Protein level used designations for HDAC2

  • YY1-associated factor 1
  • transcriptional regulator homolog RPD3
  • HD2
  • YY1 transcription factor-binding protein
  • histone deacetylase-2
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