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HDAC3 Produits

(Histone Deacetylase 3 (HDAC3))

Catégories

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].

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Catégories HDAC3 en vedette

HDAC3 Anticorps

High quality antibodies with extensive validation data.

HDAC3 Kits ELISA

Reliable ELISA kits for a wide range of species.

HDAC3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HDAC3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, IP, ChIP
Validations
  • (3)
  • (9)
N° du produit ABIN3023018
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (9)
N° du produit ABIN6256332
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (6)
N° du produit ABIN6262179
Quantité 100 μL
Fiche technique Fiche technique

HDAC3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967438
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967437
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967436
Quantité 96 tests
Fiche technique Fiche technique

HDAC3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1306448
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306450
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7425037
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HDAC3

Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." dans: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." dans: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." dans: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).

Baek, Park, Rhim, Park, Kim, Kim, Nam: "Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma." dans: Anticancer research, Vol. 36, Issue 5, pp. 2527-34, (2016) (PubMed).

Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." dans: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Liu, Lu, Zhang, Zhang, Lu, Xie, Cheng, Shen, Zhang: "C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells." dans: Biochimica et biophysica acta, Vol. 1859, Issue 2, pp. 348-54, (2016) (PubMed).

Rajendran, Dashwood, Li, Kang, Kim, Johnson, Fischer, Löhr, Williams, Ho, Yamamoto, Lieberman, Dashwood: "Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon." dans: Clinical epigenetics, Vol. 7, pp. 102, (2015) (PubMed).

Jiang, Ye, Guo, Lu, Gao: "Inhibition of HDAC3 promotes ligand-independent PPAR? activation by protein acetylation." dans: Journal of molecular endocrinology, Vol. 53, Issue 2, pp. 191-200, (2014) (PubMed).

Brodie, Li, El-Kommos, Kang, Ramalingam, Behera, Gandhi, Kowalski, Sica, Khuri, Vertino, Brandes: "Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 3, pp. 351-61, (2014) (PubMed).

Mano, Suzuki, Tsuji, Iwata: "Differential effect of HDAC3 on cytoplasmic and nuclear huntingtin aggregates." dans: PLoS ONE, Vol. 9, Issue 11, pp. e111277, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à HDAC3

Histone deacetylase 3 (HDAC3), histone deacetylase 3 (hdac3), histone deacetylase 3 (CNL05260), histone deacetylase 3 (HDAC3), histone deacetylase 3 (Hdac3), histone deacetylase 3 S homeolog (hdac3.S), AW537363, CG2128, DHDAC3, dHDAC3, Dmel\\CG2128, dmHDA402, DmHDAC3, Dromel_CG2128_FBtr0078767_hdac3_mORF, hd3, HD3, HDAC, HDAC3, Hdac 3, hdac3, HDm, RPD3, rpd3-2, RPD3-2, XRpd3, zgc:55927

Protein level used designations for HDAC3

  • CG2128-PA
  • Hdac3-PA
  • histone Deacetylase-3
  • histone deacetylase 3
  • SMAP45
  • HD3
  • HDAC3 splicing HDAC3alpha
  • HDAC3 splicing HDAC3beta
  • HDAC3 splicing HDAC3delta
  • HDAC3 splicing HDAC3gamma
  • histone deacetylase-3
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