The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Messiha, Ali, Khattab, Abo-Youssef: "Perindopril ameliorates experimental Alzheimer's disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling." dans: Inflammopharmacology, Vol. 28, Issue 5, pp. 1343-1364, (2020) (PubMed).
Zhou, Deng, Chen, Ya, Zhang, Song, Li, Yang: "Anthocyanin Cyanidin-3-Glucoside Attenuates Platelet Granule Release in Mice Fed High-Fat Diets." dans: Journal of nutritional science and vitaminology, Vol. 63, Issue 4, pp. 237-243, (2018) (PubMed).
Książek, Charmas, Klusiewicz, Zabielski, Długołęcka, Chabowski, Baranowski: "Endurance training selectively increases high-density lipoprotein-bound sphingosine-1-phosphate in the plasma." dans: Scandinavian journal of medicine & science in sports, Vol. 28, Issue 1, pp. 57-64, (2018) (PubMed).
Wu, Tang, Yu, Gao, Hu, Chen, Zheng, Yu: "Inhibitory effects of sweet cherry anthocyanins on the obesity development in C57BL/6 mice." dans: International journal of food sciences and nutrition, Vol. 65, Issue 3, pp. 351-9, (2014) (PubMed).