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Heat Shock Protein 65 (HSP65) anticorps

HSP65 Reactivité: Mycobactéries EIA, WB Hôte: Souris Monoclonal BDI578 unconjugated
N° du produit ABIN2859572
  • Antigène Tous les produits Heat Shock Protein 65 (HSP65)
    Heat Shock Protein 65 (HSP65)
    Reactivité
    Mycobactéries
    Hôte
    Souris
    Clonalité
    Monoclonal
    Application
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Specificité
    This antibody is reactive with Hsp65 (GroEL) of M. tuberculosis. Does not react with M. bovis, M. avium, M. phlei, M. parafortuitum, Rhodococcus sp., B. subtilis, S. pneumoniae, and E. coli.
    Attributs du produit
    Synonyms: 60 kDa chaperonin 2, Protein Cpn60-2, groEL protein 2, Cell wall protein A, Antigen A,groL2, groEL-2, groEL2, hsp65, Rv0440, MT0456, MTV037.04
    Purification
    Protein A chromatography
    Pureté
    > 90 % pure
    Immunogène
    Purified protein derivative (PPD)
    Clone
    BDI578
    Isotype
    IgG2a
  • Indications d'application
    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,1 mg/mL (OD280nm, E0.1% = 1.4)
    Buffer
    0.01 M PBS, pH 7.2 containing 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    Heat Shock Protein 65 (HSP65)
    Autre désignation
    Heat Shock Protein 65 / HSP65
    Synonymes
    anticorps CPN60, anticorps GROEL, anticorps HLD4, anticorps HSP-60, anticorps HSP60, anticorps HSP65, anticorps HuCHA60, anticorps SPG13, anticorps heat shock protein family D (Hsp60) member 1, anticorps HSPD1
    Sujet
    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.Synonyms: 60 kDa chaperonin 2, Antigen A, Cell wall protein A, MT0456, MTV037.04, Protein Cpn60-2, Rv0440, groEL protein 2, groEL-2, groEL2, groL2, hsp65
    ID gène
    886354
    UniProt
    P0A520
    Pathways
    Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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