Hepatitis B Virus Core Antigen Produits
(Hepatitis B Virus Core Antigen (HBcAg))
Catégories
Self assembles to form an icosahedral capsid. Most capsid appear to be large particles with a icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsid are transported along microtubules to the nucleus. Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta. Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153. Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm. Immature capsids get stucked in the basket. Capsids encapsulate the pre-genomic RNA and the P protein. Pre- genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm. The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions. {ECO:0000255|HAMAP-Rule:MF_04076}. Encapsidates hepatitis delta genome. {ECO:0000255|HAMAP- Rule:MF_04076}.
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Catégories Hepatitis B Virus Core Antigen en vedette
Hepatitis B Virus Core Antigen Anticorps
High quality antibodies with extensive validation data.
Hepatitis B Virus Core Antigen Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Hepatitis B Virus Core Antigen recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Hepatitis B Virus (HBV), Virus
Application
ELISA, IHC (p), IF (p)
Validations
- (1)
N° du produit
ABIN722991
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Hepatitis B Virus (HBV)
Application
ELISA, LF, IA, D
Validations
N° du produit
ABIN7538983
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Hepatitis B Virus (HBV)
Application
ELISA, LF, IA, D
Validations
N° du produit
ABIN7538984
Quantité
1 mg
Fiche technique
Fiche technique
Hepatitis B Virus Core Antigen recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Qualitative Sandwich ELISA
Validations
N° du produit
ABIN5025326
Quantité
96 tests
Fiche technique
Fiche technique
Hepatitis B Virus Core Antigen recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Hepatitis B Virus (HBV)
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7478071
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Hepatitis B Virus (HBV)
Source
Yeast (Pichia pastoris)
Validations
N° du produit
ABIN7478072
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Hepatitis B Virus (HBV)
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN573371
Quantité
0.5 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Hepatitis B Virus Core Antigen
: "Immunization with lentiviral vector‑modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK ..." dans: Molecular medicine reports, Vol. 18, Issue 5, pp. 4691-4699, (2019) (PubMed).: "Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model." dans: ACS infectious diseases, (2018) (PubMed).
: "Hepatitis B virus core antigen binds and activates naive human B cells in vivo: studies with a human PBL-NOD/SCID mouse model." dans: Journal of virology, Vol. 75, Issue 14, pp. 6359-66, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à Hepatitis B Virus Core Antigen
precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25 (C)Protein level used designations for Hepatitis B Virus Core Antigen
- C0 uORF
- Core antigen
- Core protein
- HBcAg
- HBe antigen
- HBeAg
- PreC
- capsid protein
- external core antigen
- p21.5
- p25
- pre-capsid protein
- precore
- precore protein
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