HFE Produits
(Hemochromatosis (HFE))
Catégories
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Catégories HFE en vedette
HFE Anticorps
High quality antibodies with extensive validation data.
HFE Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HFE recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (5)
N° du produit
ABIN561252
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, ICC
Validations
- (2)
- (4)
N° du produit
ABIN969192
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (3)
N° du produit
ABIN516405
Quantité
50 μg
Fiche technique
Fiche technique
HFE recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN1098722
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306579
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2129686
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HFE
: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." dans: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).: "Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer." dans: PLoS ONE, Vol. 8, Issue 8, pp. e74075, (2013) (PubMed).
: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." dans: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." dans: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à HFE
hemochromatosis (HFE), hemochromatosis (Hfe), HFE1, HH, HLA-H, MR2, MVCD7, TFQTL2Protein level used designations for HFE
- MHC class I-like protein HFE
- hereditary hemochromatosis protein
- hereditary hemochromatosis protein HLA-H
- high Fe
- RT1-CAFE
- hereditary hemochromatosis protein homolog
- hemochromatosis protein
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