HFE2 Produits
(Hemochromatosis Type 2 (Juvenile) (HFE2))
Catégories
The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Jul 2008].
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Catégories HFE2 en vedette
HFE2 Anticorps
High quality antibodies with extensive validation data.
HFE2 Kits ELISA
Reliable ELISA kits for a wide range of species.
HFE2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HFE2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7441934
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
N° du produit
ABIN566853
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
N° du produit
ABIN530965
Quantité
100 μg
Fiche technique
Fiche technique
HFE2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (11)
- (1)
N° du produit
ABIN6956455
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6956456
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (4)
- (1)
N° du produit
ABIN6956454
Quantité
96 tests
Fiche technique
Fiche technique
HFE2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306581
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Synthetic
Validations
- (2)
N° du produit
ABIN1880255
Quantité
200 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413832
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HFE2
: "The functional role of hemojuvelin in acute ischemic stroke." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 40, Issue 6, pp. 1316-1327, (2021) (PubMed).: "Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery." dans: Scientific reports, Vol. 8, Issue 1, pp. 1938, (2018) (PubMed).
: "Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery." dans: Critical care, Vol. 22, Issue 1, pp. 108, (2018) (PubMed).
: "Soluble hemojuvelin in transfused and untransfused thalassaemic subjects." dans: European journal of haematology, Vol. 98, Issue 1, pp. 67-74, (2017) (PubMed).
: "The secret war against counterfeit science." dans: Nature, Vol. 545, Issue 7653, pp. 148-150, (2017) (PubMed).
: "Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary Report." dans: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 24, Issue 7, pp. 1570-6, (2015) (PubMed).
: "Bone marrow iron depletion is common in patients with coronary artery disease." dans: International journal of cardiology, Vol. 182, pp. 517-22, (2015) (PubMed).
: "Iron Status and Inflammation in Early Stages of Chronic Kidney Disease." dans: Kidney & blood pressure research, Vol. 40, Issue 4, pp. 366-73, (2015) (PubMed).
: "Hemojuvelin modulates iron stress during acute kidney injury: improved by furin inhibitor." dans: Antioxidants & redox signaling, Vol. 20, Issue 8, pp. 1181-94, (2014) (PubMed).
: "The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions." dans: The Journal of surgical research, Vol. 189, Issue 1, pp. 22-31, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à HFE2
hemochromatosis type 2 (juvenile) (HFE2), hemochromatosis type 2 (juvenile) (Hfe2), hemochromatosis type 2 (hfe2), 2310035L15Rik, 5230400G09Rik, AI414844, AI789733, DKFZp468F2322, DL-M, hemojuvelin, HFE2, HFE2A, HJV, hjv, id:ibd3464, JH, RGMC, Rgmc, RGMr, wu:fb38f10, zgc:136698Protein level used designations for HFE2
- RGM domain family member C
- haemojuvelin
- hemochromatosis type 2 protein
- hemojuvelin
- repulsive guidance molecule c
- hemochromatosis type 2 (juvenile)
- hemochromatosis type 2 protein homolog
- repulsive guidance molecule C
- hemochromatosis type 2 (juvenile) (human homolog)
- RGM-like protein
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