HLA B7 Produits
(HLA Class I B7 Alpha (HLA B7))
Catégories
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories HLA B7 en vedette
HLA B7 Anticorps
High quality antibodies with extensive validation data.
HLA B7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Non-Human Primate
Application
FACS
Validations
- (6)
- (3)
N° du produit
ABIN1111104
Quantité
100 tests
Fiche technique
Fiche technique
Reactivity
Human, Non-Human Primate
Application
FACS
Validations
- (5)
- (2)
N° du produit
ABIN1027673
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Cynomolgus, Human
Application
FACS
Validations
- (1)
N° du produit
ABIN305300
Quantité
0.1 mg
Fiche technique
Fiche technique
HLA B7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2722838
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HLA B7
: "Palmitoylation of MIR2 is required for its function." dans: Journal of virology, Vol. 85, Issue 5, pp. 2288-95, (2011) (PubMed).: "Immunogenic HLA-B7-restricted peptides of hTRT." dans: International immunology, Vol. 18, Issue 12, pp. 1707-18, (2006) (PubMed).
: "Rapid and sensitive identification of major histocompatibility complex class I-associated tumor peptides by Nano-LC MALDI MS/MS." dans: Molecular & cellular proteomics : MCP, Vol. 4, Issue 12, pp. 1888-97, (2005) (PubMed).
: "Asymptomatic deficiency in the peptide transporter associated to antigen processing (TAP)." dans: Clinical and experimental immunology, Vol. 128, Issue 3, pp. 525-31, (2002) (PubMed).
: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." dans: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, (2000) (PubMed).
: "Phase I study of direct intralesional gene transfer of HLA-B7 into metastatic renal carcinoma lesions." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 10, pp. 2766-72, (1999) (PubMed).
: "Immunoradiometric assay for the rapid detection of HLA-B27." dans: Immunology and cell biology, Vol. 66 ( Pt 3), pp. 215-9, (1991) (PubMed).
: "Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 7, pp. 2361-4, (1989) (PubMed).
Synonymes et noms alternatifs relatifs à HLA B7
major histocompatibility complex, class I, B (HLA-B), AS, HLAB, SPDA1Protein level used designations for HLA B7
- HLA class I histocompatibility antigen, B alpha chain
- MHC Class I HLA heavy chain
- MHC HLA-B cell surface glycoprotein
- MHC HLA-B transmembrane glycoprotein
- MHC class I antigen GN00104
- MHC class I antigen HLA-B heavy chain
- MHC class I antigen SHCHA
- leukocyte antigen class I-B
- lymphocyte antigen
Avez-vous cherché autre chose?
Vous êtes ici:
