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HLAG Produits

(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008].

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Catégories HLAG en vedette

HLAG Anticorps

High quality antibodies with extensive validation data.

HLAG Kits ELISA

Reliable ELISA kits for a wide range of species.

HLAG Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HLAG recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (fro), IHC (p)
Validations
  • (10)
  • (5)
N° du produit ABIN94366
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (11)
  • (5)
N° du produit ABIN94373
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS, IHC (fro), IP, ICC
Validations
  • (15)
  • (4)
N° du produit ABIN94369
Quantité 0.1 mg
Fiche technique Fiche technique

HLAG recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6956586
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962367
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN809034
Quantité 96 tests
Fiche technique Fiche technique

HLAG recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7274817
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274813
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274818
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HLAG

Horii, Bui, Touma, Cho, Parast: "An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells." dans: Current protocols in stem cell biology, Vol. 50, Issue 1, pp. e96, (2020) (PubMed).

Jørgensen, Sayed, Jeppesen, Persson, Weisdorf, Funck, Hviid: "Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation." dans: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).

Vossaert, Wang, Salman, McCombs, Patel, Qu, Mancini, Edwards, Malovannaya, Liu, Shaw, Levy, Wapner, Bi, Breman, Van den Veyver, Beaudet: "Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis." dans: American journal of human genetics, Vol. 105, Issue 6, pp. 1262-1273, (2019) (PubMed).

Eche, Mackraj, Moodley: "Circulating fetal and total cell-free DNA, and sHLA-G in black South African women with gestational hypertension and pre-eclampsia." dans: Hypertension in pregnancy, Vol. 36, Issue 4, pp. 295-301, (2018) (PubMed).

Spurny, Kailayangiri, Altvater, Jamitzky, Hartmann, Wardelmann, Ranft, Dirksen, Amler, Hardes, Fluegge, Meltzer, Farwick, Greune, Rossig: "T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G." dans: Oncotarget, Vol. 9, Issue 5, pp. 6536-6549, (2018) (PubMed).

Chen, Liang, Yao, Chen, Shi, Zhang, Zhao, Zhang, Sun: "Mesenchymal stem cells upregulate Treg cells via sHLA-G in SLE patients." dans: International immunopharmacology, Vol. 44, pp. 234-241, (2017) (PubMed).

Haider, Meinhardt, Saleh, Fiala, Pollheimer, Knöfler: "Notch1 controls development of the extravillous trophoblast lineage in the human placenta." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 48, pp. E7710-E7719, (2016) (PubMed).

Liu, Hu, Zheng, Liu, Luo, Liu, Zhao, Zou: "EPHB4 Regulates Human Trophoblast Cell Line HTR-8/SVneo Function: Implications for the Role of EPHB4 in Preeclampsia." dans: Biology of reproduction, Vol. 95, Issue 3, pp. 65, (2016) (PubMed).

Guo, Lv, Wang, Shi, Yang, Zheng, Wen, Yang: "Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients." dans: Cellular immunology, Vol. 293, Issue 1, pp. 10-6, (2015) (PubMed).

Favoino, Favia, Vettori, Vicenti, Prete, Valentini, Perosa: "Clinical correlates of human leucocyte antigen (HLA)-G in systemic sclerosis." dans: Clinical and experimental immunology, Vol. 181, Issue 1, pp. 100-9, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à HLAG

major histocompatibility complex, class I, G (HLA-G), MHC BF1 class I (BF1), B-F, B-F-S04, B-F-S05, B-F-S06, B-F-S07, B-FI, B-FIV, BF2, BFa2, BFw-03, BFw-05, BFz-01, MHC-G

Protein level used designations for HLAG

  • HLA G antigen
  • HLA class I histocompatibility antigen, alpha chain G
  • HLA class I molecule
  • HLA-G histocompatibility antigen, class I, G
  • MHC class I antigen G
  • b2 microglobulin
  • B-F minor
  • MHC class I antigen alpha chain
  • MHC class I glycoprotein
  • major histocompatibility complex, class I, G
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