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HMGA2 Produits

(High Mobility Group AT-Hook 2 (HMGA2))

Catégories

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Catégories HMGA2 en vedette

HMGA2 Anticorps

High quality antibodies with extensive validation data.

HMGA2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (3)
N° du produit ABIN6243228
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (1)
  • (2)
N° du produit ABIN1981306
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF
Validations
  • (2)
N° du produit ABIN6243227
Quantité 400 μL
Fiche technique Fiche technique

HMGA2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7497089
Quantité 200 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HMGA2

Zhu, Xiao, Wang, Hu, Duan, Zhu, Gao, Zhu, Wang: "MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness." dans: Journal of neurosurgery, pp. 1-13, (2020) (PubMed).

Luo, Li, Ge, Mei, Zhao, Jiang, Geng, Li, Yao, Cao: "HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." dans: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).

DiMaio, Weis-Garcia, Bagiella, Tang, Allen: "Pancreatic cyst fluid concentration of high-mobility group A2 protein acts as a differential biomarker of dysplasia in intraductal papillary mucinous neoplasm." dans: Gastrointestinal endoscopy, Vol. 83, Issue 6, pp. 1205-9, (2016) (PubMed).

Xu, Zhu, Guo, Jiang, Hussain, Meng, Lu: "Construction of Conveniently Screening pLKO.1-TRC Vector Tagged with TurboGFP." dans: Applied biochemistry and biotechnology, (2016) (PubMed).

Li, Peng, Seto: "Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway." dans: Molecular and cellular biology, Vol. 35, Issue 20, pp. 3547-65, (2015) (PubMed).

Di Cello, Hillion, Hristov, Wood, Mukherjee, Schuldenfrei, Kowalski, Bhattacharya, Ashfaq, Resar: "HMGA2 participates in transformation in human lung cancer." dans: Molecular cancer research : MCR, Vol. 6, Issue 5, pp. 743-50, (2008) (PubMed).

Hebert, Norris, Scheper, Nikitakis, Sauk: "High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma." dans: Molecular cancer, Vol. 6, pp. 5, (2007) (PubMed).

Patel, Bandiera, Manfioletti, Giancotti, Chau, Crane-Robinson: "Expression and cDNA cloning of human HMGI-C phosphoprotein." dans: Biochemical and biophysical research communications, Vol. 201, Issue 1, pp. 63-70, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à HMGA2

high mobility group AT-hook 2 (Hmga2), high mobility group AT-hook 2 (hmga2), high mobility group AT-hook 2 (HMGA2), 9430083A20Rik, BABL, HMGI-C, Hmgic, HMGIC, LIPO, pg, pygmy, STQTL9, wu:fc27f12, wu:fc28f02, wu:fc57d12, zgc:77719

Protein level used designations for HMGA2

  • high mobility group AT-hook protein 2
  • high mobility group protein HMGI-C
  • high mobility group protein I
  • non-histone chromosomal architectural protein HMGI-C
  • high mobility group protein I-C
  • likely candidate for the autosomal dwarf locus in the chicken
  • High-mobility group protein HMGI-C
  • high-mobility group (nonhistone chromosomal) protein isoform I-C
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