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HNRNPK Produits

(Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Catégories

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference\; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008].

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Catégories HNRNPK en vedette

HNRNPK Anticorps

High quality antibodies with extensive validation data.

HNRNPK Kits ELISA

Reliable ELISA kits for a wide range of species.

HNRNPK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HNRNPK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (12)
N° du produit ABIN3022414
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (7)
N° du produit ABIN2855169
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF, IP
Validations
  • (5)
N° du produit ABIN7127548
Quantité 100 μL
Fiche technique Fiche technique

HNRNPK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956515
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967386
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380450
Quantité 2 x 96 tests
Fiche technique Fiche technique

HNRNPK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1306879
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (1)
N° du produit ABIN1047168
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN2722924
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HNRNPK

Cao, Zhang, Li, Wu: "LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells." dans: eLife, Vol. 6, (2018) (PubMed).

Yang, Zeng, Xu, Chen, Xiang, Fu, Yin, Zhong, Zeng, Wang, You, Zeng: "Heterogeneous nuclear ribonucleoprotein K is overexpressed and associated with poor prognosis in gastric cancer." dans: Oncology reports, Vol. 36, Issue 2, pp. 929-35, (2016) (PubMed).

Moujalled, James, Yang, Zhang, Duncan, Moujalled, Parker, Caragounis, Lidgerwood, Turner, Atkin, Grubman, Liddell, Proepper, Boeckers, Kanninen, Blair, Crouch, White: "Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43." dans: Human molecular genetics, Vol. 24, Issue 6, pp. 1655-69, (2015) (PubMed).

Chung, Arutyunov, Ilagan, Yao, Wills-Karp, Coulombe: "Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes." dans: The Journal of cell biology, Vol. 208, Issue 5, pp. 613-27, (2015) (PubMed).

Yoon, McKenna, Rollins, Song, Nuriel, Gross, Xu, Glatt: "Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11624-9, (2013) (PubMed).

Yang, Chevolot, Géhin, Solassol, Mange, Souteyrand, Laurenceau: "Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera." dans: Biosensors & bioelectronics, Vol. 40, Issue 1, pp. 385-92, (2012) (PubMed).

Proepper, Steinestel, Schmeisser, Heinrich, Steinestel, Bockmann, Liebau, Boeckers: "Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27045, (2011) (PubMed).

Li, Liu: "Identification of heterogeneous nuclear ribonucleoprotein K as a transactivator for human low density lipoprotein receptor gene transcription." dans: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17789-97, (2010) (PubMed).

Huarte, Guttman, Feldser, Garber, Koziol, Kenzelmann-Broz, Khalil, Zuk, Amit, Rabani, Attardi, Regev, Lander, Jacks, Rinn: "A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response." dans: Cell, Vol. 142, Issue 3, pp. 409-19, (2010) (PubMed).

Sakai, Sakamoto, Fujita, Ishizuka: "The importance of heterogeneous nuclear ribonucleoprotein K on cytochrome P450 2D2 gene regulation: its binding is reduced in Dark Agouti rats." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 8, pp. 1703-10, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à HNRNPK

heterogeneous nuclear ribonucleoprotein K (HNRNPK), heterogeneous nuclear ribonucleoprotein K (Hnrnpk), heterogeneous nuclear ribonucleoprotein K S homeolog (hnrnpk.S), heterogeneous nuclear ribonucleoprotein K (hnrnpk), heterogeneous nuclear ribonucleoprotein K (LOC5565718), heterogeneous nuclear ribonucleoprotein k (CpipJ_CPIJ000130), heterogeneous nuclear ribonucleoprotein K (NGK_p0004), CSBP, Csbp, HNRPK, Hnrpk, hnrpk, KBBP, MGC75642, NOVA, TUNP, wu:fb37h02, wu:fi34c04, zgc:66162

Protein level used designations for HNRNPK

  • dC-stretch binding protein
  • transformation upregulated nuclear protein
  • dC stretch-binding protein
  • hnRNP K
  • heterogeneous nuclear ribonucleoprotein K
  • heterogeneous nuclear ribonucleoprotein k
  • hnRNP-K protein
  • heterogeneous nuclear ribonucleoprotein K-like
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