HSD11B1 Produits
(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
Catégories
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Catégories HSD11B1 en vedette
HSD11B1 Anticorps
High quality antibodies with extensive validation data.
HSD11B1 Kits ELISA
Reliable ELISA kits for a wide range of species.
HSD11B1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HSD11B1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Horse, Human, Mouse, Rat
Application
ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (2)
- (4)
N° du produit
ABIN750913
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
N° du produit
ABIN7218624
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application
WB, IHC
Validations
- (2)
- (5)
N° du produit
ABIN2773867
Quantité
100 μL
Fiche technique
Fiche technique
HSD11B1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6956632
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6956634
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967494
Quantité
96 tests
Fiche technique
Fiche technique
HSD11B1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123384
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1307101
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396115
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HSD11B1
: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." dans: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).: "Synthesis of the N-methyl Derivatives of 2-Aminothiazol-4(5H)-one and Their Interactions with 11βHSD1-Molecular Modeling and in Vitro Studies." dans: Chemistry & biodiversity, Vol. 16, Issue 6, pp. e1900065, (2019) (PubMed).
: "A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1." dans: Bioorganic chemistry, Vol. 79, pp. 115-121, (2019) (PubMed).
: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." dans: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
: "Local cortisol activation is involved in EGF-induced immunosuppression." dans: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." dans: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).
: "Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis." dans: Molecules (Basel, Switzerland), Vol. 21, Issue 11, (2016) (PubMed).
: "Anti-Inflammatory Property of Plantago major Leaf Extract Reduces the Inflammatory Reaction in Experimental Acetaminophen-Induced Liver Injury." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 347861, (2015) (PubMed).
: "A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11?-hydroxysteroid dehydrogenase-1 expression in the offspring." dans: PLoS ONE, Vol. 9, Issue 1, pp. e84125, (2014) (PubMed).
: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." dans: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à HSD11B1
hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1), hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b), hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L), hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), 11-beta-HSD1, 11-DH, CORTRD2, HDL, HSD11, hsd11, HSD11B, hsd11b, HSD11L, LRRGT00065, SDR26C1Protein level used designations for HSD11B1
- 11-beta-hydroxysteroid dehydrogenase 1
- hydroxysteroid 11-beta dehydrogenase 1
- hydroxysteroid (11-beta) dehydrogenase 1
- corticosteroid 11-beta-dehydrogenase isozyme 1
- short chain dehydrogenase/reductase family 26C, member 1
- 11-DH
- 11-beta-HSD1
- 11-beta-hydroxysteroid dehydrogenase type 1
- 11-beta hydroxysteroid dehydrogenase
- 11 beta-hydroxysteroid dehydrogenase type 1
- 7-alpha-HCD
- 7-alpha-hydroxycholesterol dehydrogenase
- 11beta-HSD-1
- 11beta-HSD1A
- 11beta-hydroxysteroid dehydrogenase type 1
- Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A)
- cortocosteroid 11-beta dehydrogenase
- hydroxysteroid dehydrogenase, 11 beta type 1
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