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HSD17B4 Produits

(Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Catégories

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008].

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Catégories HSD17B4 en vedette

HSD17B4 Anticorps

High quality antibodies with extensive validation data.

HSD17B4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HSD17B4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (1)
  • (5)
N° du produit ABIN2855717
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (4)
N° du produit ABIN2856979
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
N° du produit ABIN3031274
Quantité 100 μg
Fiche technique Fiche technique

HSD17B4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3078925
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3134367
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Yeast
Validations
  • (1)
N° du produit ABIN5713516
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HSD17B4

Eun, Lee, Nam, Liu, So, Choe, Park: "PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation." dans: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 4, (2019) (PubMed).

Zhu, Chen, Wang, Elsherbini, Zhong, Jiang, Qin, Tripathi, Zhi, Spassieva, Morris, Bieberich: "Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1514-1524, (2019) (PubMed).

Dávalos-Salas, Montgomery, Reehorst, Nightingale, Ng, Anderton, Al-Obaidi, Lesmana, Scott, Ioannidis, Kalra, Keerthikumar, Tögel, Rigopoulos, Gong, Williams, Yoganantharaja, Bell-Anderson, Mathivanan et al.: "Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. ..." dans: Nature communications, Vol. 10, Issue 1, pp. 5291, (2019) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Maier, Luks, Baudendistel, Wittmann, Dietrich: "Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy." dans: Chemico-biological interactions, Vol. 281, pp. 69-80, (2018) (PubMed).

Frasinyuk, Zhang, Wyrebek, Yu, Xu, Sviripa, Bondarenko, Xie, Ngo, Morris, Mohler, Fiandalo, Watt, Liu: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." dans: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).

Naudí, Cabré, Dominguez-Gonzalez, Ayala, Jové, Mota-Martorell, Piñol-Ripoll, Gil-Villar, Rué, Portero-Otín, Ferrer, Pamplona: "Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system." dans: Biochimica et biophysica acta, Vol. 1862, Issue 5, pp. 485-495, (2017) (PubMed).

Cabré, Naudí, Dominguez-Gonzalez, Jové, Ayala, Mota-Martorell, Pradas, Nogueras, Rué, Portero-Otín, Ferrer, Pamplona: "Lipid Profile in Human Frontal Cortex is Sustained Throughout Healthy Adult Lifespan to Decay at Advanced Ages." dans: The journals of gerontology. Series A, Biological sciences and medical sciences (PubMed).

Synonymes et noms alternatifs relatifs à HSD17B4

hydroxysteroid (17-beta) dehydrogenase 4 (hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), peroxisomal Multifunctional enzyme type 2 (Mfe2), hydroxysteroid (17-beta) dehydrogenase 4 (Hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (Hsd17b4), 4, 17-beta-HSD, 17[b]-HSD, CG3415, DBP, Dmel\\CG3415, DmMFE-2, MFE-2, Mfp-2, MFP2, MPF-2, perMFE-2, PRLTS1, SDR8C1, zgc:55545, zgc:77300

Protein level used designations for HSD17B4

  • peroxisomal multifunctional enzyme type 2
  • CG3415-PA
  • Mfe2-PA
  • 17-beta-HSD 4
  • 17-beta-HSD IV
  • 17-beta-hydroxysteroid dehydrogenase 4
  • 17beta-estradiol dehydrogenase type IV
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
  • D-3-hydroxyacyl-CoA dehydratase
  • D-bifunctional protein, peroxisomal
  • beta-hydroxyacyl dehydrogenase
  • beta-keto-reductase
  • multifunctional protein 2
  • peroxisomal multifunctional protein 2
  • short chain dehydrogenase/reductase family 8C, member 1
  • D-bifunctional protein
  • DBP
  • MFE-2
  • peroxisomal multifunctional enzyme type II
  • 17-beta-hydroxysteroid dehydrogenase type IV
  • 17beta-estradiol dehydrogenase
  • mutifunctional protein2
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