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HUWE1 Produits

(HECT, UBA and WWE Domain Containing 1, E3 Ubiquitin Protein Ligase (HUWE1))
This gene encodes a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains\; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung, breast, and colorectal carcinomas, this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation, Turner type. [provided by RefSeq, Nov 2009].

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Catégories HUWE1 en vedette

HUWE1 Anticorps

High quality antibodies with extensive validation data.

HUWE1 Kits ELISA

Reliable ELISA kits for a wide range of species.

HUWE1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HUWE1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN213933
Quantité 0.05 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7248203
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN564354
Quantité 50 μL
Fiche technique Fiche technique

HUWE1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967324
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967325
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967323
Quantité 96 tests
Fiche technique Fiche technique

HUWE1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307296
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Yeast
Validations
N° du produit ABIN1474622
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HUWE1

Suzuki, Okamoto, Katoh, Sugiyama, Kusakabe, Tokunaga, Hirano, Miyata, Fukuhara, Ikawa, Satoh, Yoshio, Suzuki, Saijo, Huang, Kanto, Akira, Matsuura: "Infection with flaviviruses requires BCLXL for cell survival." dans: PLoS pathogens, Vol. 14, Issue 9, pp. e1007299, (2019) (PubMed).

Crow, Cristea: "Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation." dans: Molecular & cellular proteomics : MCP, Vol. 16, Issue 4 suppl 1, pp. S200-S214, (2017) (PubMed).

Cheng, Tong, Edge: "Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development." dans: The Journal of biological chemistry, Vol. 291, Issue 40, pp. 21096-21109, (2016) (PubMed).

Choe, Nicolae, Constantin, Imamura Kawasawa, Delgado-Diaz, De, Freire, Smits, Moldovan: "HUWE1 interacts with PCNA to alleviate replication stress." dans: EMBO reports, Vol. 17, Issue 6, pp. 874-86, (2016) (PubMed).

Katsogiannou, Andrieu, Baylot, Baudot, Dusetti, Gayet, Finetti, Garrido, Birnbaum, Bertucci, Brun, Rocchi: "The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets." dans: Molecular & cellular proteomics : MCP, Vol. 13, Issue 12, pp. 3585-601, (2014) (PubMed).

Kon, Zhong, Qiang, Accili, Gu: "Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice." dans: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 5102-11, (2012) (PubMed).

Markkanen, van Loon, Ferrari, Parsons, Dianov, Hübscher: "Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 2, pp. 437-42, (2012) (PubMed).

Mandel, Paperna, Miller: "Aberrant expression of the apoptosis-related proteins BAK and MCL1 in T cells in multiple sclerosis." dans: Journal of neuroimmunology, Vol. 244, Issue 1-2, pp. 51-6, (2012) (PubMed).

Noy, Suad, Taglicht, Ciechanover: "HUWE1 ubiquitinates MyoD and targets it for proteasomal degradation." dans: Biochemical and biophysical research communications, Vol. 418, Issue 2, pp. 408-13, (2012) (PubMed).

Rolfo, Garcia, Todros, Post, Caniggia: "The double life of MULE in preeclamptic and IUGR placentae." dans: Cell death & disease, Vol. 3, pp. e305, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à HUWE1

HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (HUWE1), HECT, UBA and WWE domain containing 1 (Huwe1), HECT, UBA and WWE domain containing 1 (huwe1), HECT, UBA and WWE domain containing 1 (LOC100123214), HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (huwe1), E3 ubiquitin-protein ligase HUWE1 (LOC100380641), HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (Huwe1), 5430439H10Rik, ARF-BP1, Arf-bp1, arf-bp1, AU041296, C80292, C430014N20Rik, Gm1718, HECTH9, hecth9, HSPC272, hspc272, HUWE1, Huwe1, Ib772, ib772, LASU1, lasu1, MULE, Mule, mule, si:dkey-242a8.2, URE-B1, UREB1, Ureb1, ureb1

Protein level used designations for HUWE1

  • ARF-binding protein 1
  • BJ-HCC-24 tumor antigen
  • E3 ubiquitin-protein ligase HUWE1
  • HECT domain protein LASU1
  • Mcl-1 ubiquitin ligase E3
  • URE-binding protein 1
  • homologous to E6AP carboxyl terminus homologous protein 9
  • large structure of UREB1
  • upstream regulatory element-binding protein 1
  • E3Histone
  • HECT, UBA and WWE domain-containing protein 1
  • Mcl-1 ubiquitin ligase
  • URE-B1
  • upstream regulatory element binding protein 1
  • HECT, UBA and WWE domain containing 1
  • rp3-339a18.4
  • e3 ubiquitin-protein ligase HUWE1-like
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