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HYAL2 Produits

(Hyaluronidase-2 (HYAL2))
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010].

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Catégories HYAL2 en vedette

HYAL2 Anticorps

High quality antibodies with extensive validation data.

HYAL2 Kits ELISA

Reliable ELISA kits for a wide range of species.

HYAL2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HYAL2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN654687
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7436957
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
N° du produit ABIN7155971
Quantité 100 μL
Fiche technique Fiche technique

HYAL2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967482
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967483
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN581358
Quantité 96 tests
Fiche technique Fiche technique

HYAL2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123374
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307302
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7504422
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HYAL2

Kong, Ordoñez, Turner, Tremaine, Muter, Lucas, Salisbury, Vassena, Tiscornia, Fouladi-Nashta, Hartshorne, Brosens, Brighton: "Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 35, Issue 4, pp. e21336, (2021) (PubMed).

Panogeorgou, Tserbini, Filou, Vynios, Naxakis, Papadas, Goumas, Mastronikolis: "Hyaluronan synthases and hyaluronidases in nasal polyps." dans: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 273, Issue 7, pp. 1801-8, (2016) (PubMed).

Monzon, Fregien, Schmid, Falcon, Campos, Casalino-Matsuda, Forteza: "Reactive oxygen species and hyaluronidase 2 regulate airway epithelial hyaluronan fragmentation." dans: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26126-34, (2010) (PubMed).

Monzón, Manzanares, Schmid, Casalino-Matsuda, Forteza: "Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells." dans: American journal of respiratory cell and molecular biology, Vol. 39, Issue 3, pp. 289-95, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à HYAL2

hyaluronoglucosaminidase 2 S homeolog (hyal2.S), hyaluronoglucosaminidase 2 (HYAL2), hyaluronoglucosaminidase 2b (hyal2b), hyaluronoglucosaminidase 2 (hyal2), hyaluronoglucosaminidase 2 L homeolog (hyal2.L), hyaluronoglucosaminidase 2 (Hyal2), AI256841, AU020858, AW555733, hyal2, hyal2a, hyal2b, luca-2, luca2, LUCA2, oHyal2, si:dkey-42i9.14, xhyal2

Protein level used designations for HYAL2

  • hyaluronidase 2 b
  • hyaluronoglucosaminidase 2
  • hyaluronidase-2
  • hyaluronidase 2
  • hyaluronidase 2 a
  • hyaluronidase-2-like
  • PH-20 homolog
  • PH20 homolog
  • hyal-2
  • hyaluronoglucosaminidase-2
  • lung carcinoma protein 2
  • lysosomal hyaluronidase
  • GPI-anchored surface protein
  • JSRV envelope protein receptor
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