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IDH3A Produits

(Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Catégories

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008].

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Catégories IDH3A en vedette

IDH3A Anticorps

High quality antibodies with extensive validation data.

IDH3A Kits ELISA

Reliable ELISA kits for a wide range of species.

IDH3A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IDH3A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (8)
N° du produit ABIN7258018
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN7268029
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (5)
N° du produit ABIN2855763
Quantité 100 μL
Fiche technique Fiche technique

IDH3A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6205396
Quantité 96 tests
Fiche technique Fiche technique

IDH3A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307374
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2723870
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Pig
Source Yeast
Validations
N° du produit ABIN1472581
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits IDH3A

Zhang, Wang, Shi, Liu, Sun, Hou, Zhang, Zhao, Zhou, Mi: "Metabolic reprogramming of cancer-associated fibroblasts by IDH3? downregulation." dans: Cell reports, Vol. 10, Issue 8, pp. 1335-48, (2015) (PubMed).

Xing, Yuan, Xu, Gu, Liang, Lu: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." dans: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, (2015) (PubMed).

Lin, Cheng, Tsai, Tsai, Hu, Chang, Yeh, Chen, Liao, Chang: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." dans: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).

Soundar, Park, Huh, Colman: "Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase." dans: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52146-53, (2003) (PubMed).

Kim, Koh, Kim, Jo, Huh, Jeong, Lee, Song, Huh: "Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform." dans: The Journal of biological chemistry, Vol. 274, Issue 52, pp. 36866-75, (2000) (PubMed).

Weiss, Zeng, Huang, Sobocka, Rushbrook: "Bovine NAD+-dependent isocitrate dehydrogenase: alternative splicing and tissue-dependent expression of subunit 1." dans: Biochemistry, Vol. 39, Issue 7, pp. 1807-16, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à IDH3A

isocitrate dehydrogenase 3 (NAD+) alpha (idh3a), isocitrate dehydrogenase 3 (NAD(+)) alpha (IDH3A), isocitrate dehydrogenase 3 (NAD(+)) alpha (idh3a), isocitrate dehydrogenase 3 (NAD+) alpha S homeolog (idh3a.S), isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), 1110003P10Rik, 1500012E04Rik, AA407078, AI316514, BG1, idh3a, IDH3A, MGC76128, zgc:56380, zgc:85631

Protein level used designations for IDH3A

  • isocitrate dehydrogenase 3 (NAD+) alpha
  • isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
  • mitochondrial isocitrate dehydrogenase (nad) subunit alpha
  • H-IDH alpha
  • NAD(+)-specific ICDH subunit alpha
  • NAD(H)-specific isocitrate dehydrogenase alpha subunit
  • NAD+-specific ICDH
  • isocitrate dehydrogenase (NAD+) alpha chain
  • isocitric dehydrogenase subunit alpha
  • isocitrate dehydrogenase subunits 3/4
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