IDO Produits
(Indoleamine 2,3-Dioxygenase (IDO))
Catégories
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].
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Catégories IDO en vedette
IDO Anticorps
High quality antibodies with extensive validation data.
IDO Kits ELISA
Reliable ELISA kits for a wide range of species.
IDO Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IDO recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7433768
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7426307
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (3)
N° du produit
ABIN5013734
Quantité
100 μL
Fiche technique
Fiche technique
IDO recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (10)
- (6)
N° du produit
ABIN6574282
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
N° du produit
ABIN6730945
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6956720
Quantité
96 tests
Fiche technique
Fiche technique
IDO recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN6239816
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN4371986
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN4371989
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IDO
: "Proteinuria is Associated with Urinary Loss of Cubilin and Vitamin D-Binding Protein in Patients with Preeclampsia." dans: Scientific reports, Vol. 10, Issue 1, pp. 3956, (2020) (PubMed).: "Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors." dans: Journal of neuro-oncology, Vol. 139, Issue 2, pp. 239-249, (2019) (PubMed).
: "Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression." dans: International immunopharmacology, Vol. 73, pp. 527-538, (2019) (PubMed).
: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." dans: Molecular imaging, Vol. 15, (2016) (PubMed).
: "Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase." dans: PLoS ONE, Vol. 11, Issue 10, pp. e0163709, (2016) (PubMed).
: "Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection." dans: Nature communications, Vol. 6, pp. 8608, (2016) (PubMed).
: "Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes." dans: Apoptosis : an international journal on programmed cell death, (2015) (PubMed).
: "Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation." dans: Frontiers in oncology, Vol. 5, pp. 87, (2015) (PubMed).
: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." dans: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).
: "Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma." dans: Hepatology (Baltimore, Md.), Vol. 59, Issue 2, pp. 567-79, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à IDO
indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 (Ido1), IDO, Ido, IDO-1, INDO, IndoProtein level used designations for IDO
- indolamine 2,3 dioxygenase
- indole 2,3-dioxygenase
- indoleamine-pyrrole 2,3-dioxygenase
- IDO-1
- indoleamine-pyrrole 2,3 dioxygenase
- indoleamine 23-dioxygenase
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