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IGF2R Produits

(Insulin-Like Growth Factor 2 Receptor (IGF2R))
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013].

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Catégories IGF2R en vedette

IGF2R Anticorps

High quality antibodies with extensive validation data.

IGF2R Kits ELISA

Reliable ELISA kits for a wide range of species.

IGF2R Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IGF2R recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Non-Human Primate
Application WB, FACS, IP
Validations
  • (2)
  • (4)
N° du produit ABIN94039
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (5)
N° du produit ABIN7267905
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (5)
N° du produit ABIN5693085
Quantité 100 μg
Fiche technique Fiche technique

IGF2R recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967650
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956801
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN2703119
Quantité 96 tests
Fiche technique Fiche technique

IGF2R recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123457
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307559
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
N° du produit ABIN1046788
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IGF2R

Gerber, Mosser, Boury-Jamot, Stumpe, Piersigilli, Goepfert, Dengjel, Albrecht, Magara, Fraering: "The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease." dans: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 13, (2019) (PubMed).

Godoy-Parejo, Deng, Liu, Chen: "Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells." dans: Stem cells (Dayton, Ohio), Vol. 37, Issue 8, pp. 1030-1041, (2019) (PubMed).

Kakegawa, Katoh, Narumi, Miura, Motohashi, Takahashi, Kohda, Fukazawa, Yuzaki, Matsuda: "Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning." dans: Neuron, Vol. 99, Issue 5, pp. 985-998.e6, (2018) (PubMed).

Mu, Zhang, Wang, Xu, Ahmed, Pang, Chibbar, Freywald, Huang, Zhu, Xiang: "Enhanced suppression of polyclonal CD8+25+regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes." dans: Journal of leukocyte biology, Vol. 101, Issue 5, pp. 1221-1231, (2017) (PubMed).

Ahmed, Xiang: "mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A." dans: Cell discovery, Vol. 3, pp. 17011, (2017) (PubMed).

Liu, Yu, Wu, Sun, Su, You, Xin: "CD44+fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1979-1988, (2017) (PubMed).

Martín-Montañez, Millon, Boraldi, Garcia-Guirado, Pedraza, Lara, Santin, Pavia, Garcia-Fernandez: "IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids." dans: Redox biology, Vol. 13, pp. 69-81, (2017) (PubMed).

Takahashi, Mashima, Miura, Maeda, Goto, Goto, Sun-Wada, Wada, Ohnishi: "Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models." dans: Scientific reports, Vol. 7, Issue 1, pp. 2817, (2017) (PubMed).

Chanprasertyothin, Jongjaroenprasert, Ongphiphadhanakul: "The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes." dans: Journal of diabetes research, Vol. 2015, pp. 216383, (2015) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." dans: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à IGF2R

insulin like growth factor 2 receptor (IGF2R), insulin-like growth factor 2 receptor (Igf2r), insulin like growth factor 2 receptor (igf2r), AI661837, CD222, cd222, CI-MPR, CIMPR, cimpr, M6P-R, m6p-r, M6P/IGF2R, MPR1, Mpr300, MPRI, mpri

Protein level used designations for IGF2R

  • 300 kDa mannose 6-phosphate receptor
  • CI Man-6-P receptor
  • CI-MPR
  • IGF-II receptor
  • M6P/IGF2 receptor
  • M6P/IGF2R
  • M6PR
  • MPR 300
  • cation-independent mannose-6 phosphate receptor
  • cation-independent mannose-6-phosphate receptor
  • insulin-like growth factor II receptor
  • IGF-II/CI-MPR
  • cation-independent MPR
  • cation-independent mannose 6-phosphate receptor
  • mannose-6-phosphate receptor, cation independent
  • insulin-like growth factor receptor type 2
  • cation-independent mannose 6 phosphate receptor
  • insulin-like growth factor 2 receptor
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