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IKBKG Produits

(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011].

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Catégories IKBKG en vedette

IKBKG Anticorps

High quality antibodies with extensive validation data.

IKBKG Kits ELISA

Reliable ELISA kits for a wide range of species.

IKBKG Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IKBKG recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
  • (7)
N° du produit ABIN3021151
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p), PLA
Validations
  • (6)
N° du produit ABIN563664
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
N° du produit ABIN7189515
Quantité 100 μg
Fiche technique Fiche technique

IKBKG recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6967600
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956745
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380483
Quantité 2 x 96 tests
Fiche technique Fiche technique

IKBKG recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123431
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123432
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123433
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IKBKG

Sakowicz, Lisowska, Biesiada, Płuciennik, Gach, Rybak-Krzyszkowska, Huras, Sakowicz, Romanowicz, Piastowska-Ciesielska, Grzesiak, Pietrucha: "Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia." dans: Disease markers, Vol. 2019, pp. 8418379, (2019) (PubMed).

Alameda, Ramírez, García-Fernández, Navarro, Page, Segovia, Sanchez, Suárez-Cabrera, Paramio, Bravo, Fernández-Aceñero, Casanova: "Premature aging and cancer development in transgenic mice lacking functional CYLD." dans: Aging, Vol. 11, Issue 1, pp. 127-159, (2019) (PubMed).

Zhu, Fang, Wang, Yang, Chen, Ye, Foda, Xiao: "Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO." dans: Virology, Vol. 502, pp. 33-38, (2017) (PubMed).

Zhou, Yu, Demirkaya, Deuitch, Stone, Tsai, Kuehn, Wang, Yang, Park, Ombrello, Blake, Romeo, Remmers, Chae, Mullikin, Güzel, Milner, Boehm, Rosenzweig, Gadina, Welch, Özen, Topaloglu, Abinun, Kastner et al.: "Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 36, pp. 10127-32, (2016) (PubMed).

Guo, Hu, Chen, Li, Ye, Cheng, Zhang, He: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." dans: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).

Ren, Takahashi, Liu, Loughran, Sun, Wang, Cheng: "HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains." dans: Oncogene, Vol. 34, Issue 3, pp. 334-45, (2015) (PubMed).

Konrath, Witt, Sauter, Kulms: "Identification of new IκBα complexes by an iterative experimental and mathematical modeling approach." dans: PLoS computational biology, Vol. 10, Issue 3, pp. e1003528, (2014) (PubMed).

Wang, Fang, Wei, Zhang, Luo, Chen, Li, Xiao: "Hepatitis A virus 3C protease cleaves NEMO to impair induction of beta interferon." dans: Journal of virology, Vol. 88, Issue 17, pp. 10252-8, (2014) (PubMed).

Fusco, DUrso, Miano, Ursini: "The LCR at the IKBKG locus is prone to recombine." dans: American journal of human genetics, Vol. 86, Issue 4, pp. 650-2; author reply 652-3, (2010) (PubMed).

Hsiao, Lin, Chiang, Wu, Chen, Lin: "NEMO gene mutations in Chinese patients with incontinentia pigmenti." dans: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 109, Issue 3, pp. 192-200, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à IKBKG

inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), inhibitor of kappaB kinase gamma (Ikbkg), inhibitor of nuclear factor kappa B kinase subunit gamma (Ikbkg), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (ikbkg), inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog (ikbkg.L), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG_1), inhibitor of nuclear factor kappa B kinase subunit gamma (ikbkg), kenny (key), 1110037D23Rik, AI848108, AI851264, AMCBX1, AW124339, CG16910, dIKK, dIKK-gamma, Dmel\\CG16910, DmIKK-gamma, DmIKKgamma, Dmikkgamma, dmIKKgamma, FIP-3, FIP3, Fip3p, fj33c07, IKBKG, IKBKG_1, IKBKG_2, IKK, IKK-gamma, IKKg, IKKgamma, IKK[g], IKK[[gamma]], IP, IP1, IP2, IPD2, Kenny, KEY, Key, MGC97885, NEMO, Nemo, nemo, wu:fj33c07, ZC2HC9, zgc:113492

Protein level used designations for IKBKG

  • I-kappa-B kinase subunit gamma
  • IKKAP1
  • IKKG
  • IkB kinase gamma subunit
  • NF-kappa-B essential modifier
  • NF-kappa-B essential modulator
  • NFkappaB essential modulator
  • ikB kinase subunit gamma
  • ikB kinase-associated protein 1
  • incontinentia pigmenti
  • inhibitor of nuclear factor kappa-B kinase subunit gamma
  • IKK-gamma
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • mFIP-3
  • I-kappa-B kinase gamma
  • NEMO
  • NF-kappa B essential modulator
  • inhibitor of kappaB kinase gamma
  • ikky
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 1
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 2
  • NF-kappa-B essential modulator-like
  • CG16910-PA
  • CG16910-PB
  • key-PA
  • key-PB
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