IL-10RA Produits
(Interleukin 10 Receptor, alpha (IL10RA))
Catégories
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].
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Catégories IL-10RA en vedette
IL-10RA Anticorps
High quality antibodies with extensive validation data.
IL-10RA Kits ELISA
Reliable ELISA kits for a wide range of species.
IL-10RA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL-10RA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7433870
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN3022615
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7259833
Quantité
200 μL
Fiche technique
Fiche technique
IL-10RA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956986
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956987
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956988
Quantité
96 tests
Fiche technique
Fiche technique
IL-10RA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7274906
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7274878
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN6253272
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL-10RA
: "Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9." dans: BMC genetics, Vol. 21, Issue 1, pp. 121, (2020) (PubMed).: "MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade." dans: International immunopharmacology, Vol. 64, pp. 394-400, (2019) (PubMed).
: "Enhanced gut barrier integrity sensitizes colon cancer to immune therapy." dans: Oncoimmunology, Vol. 7, Issue 11, pp. e1498438, (2018) (PubMed).
: "Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma." dans: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16686-98, (2016) (PubMed).
: "cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells." dans: PLoS ONE, Vol. 9, Issue 2, pp. e88708, (2014) (PubMed).
: "Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27464, (2011) (PubMed).
: "Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 3, pp. 1240-8, (2003) (PubMed).
: "Regulatory activity of autocrine IL-10 on dendritic cell functions." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4312-8, (2001) (PubMed).
: "Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6087-91, (2001) (PubMed).
: "IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways." dans: The EMBO journal, Vol. 17, Issue 4, pp. 1006-18, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à IL-10RA
interleukin 10 receptor subunit alpha (IL10RA), interleukin 10 receptor, alpha (Il10ra), interleukin 10 receptor subunit alpha (Il10ra), AW553859, CD210, CD210a, CDw210, CDW210A, CDw210a, HIL-10R, IL-10R1, IL10R, Il10r, IL10R1, IL10RA, mIL-10RProtein level used designations for IL-10RA
- interleukin 10 receptor 1
- interleukin-10 receptor subunit alpha
- interleukin 10 receptor, alpha
- interleukin-10 receptor subunit alpha-like
- IL-10 receptor subunit alpha
- IL-10R subunit 1
- IL-10R subunit alpha
- IL-10RA
- interleukin-10 receptor alpha chain
- interleukin-10 receptor subunit 1
- IL-10R1
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