IL-6 Receptor Produits
(Interleukin 6 Receptor (IL6R))
Catégories
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
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Catégories IL-6 Receptor en vedette
IL-6 Receptor Anticorps
High quality antibodies with extensive validation data.
IL-6 Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
IL-6 Receptor Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL-6 Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN7234279
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN3015522
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7434104
Quantité
100 μL
Fiche technique
Fiche technique
IL-6 Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
N° du produit
ABIN6720572
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6730982
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957177
Quantité
96 tests
Fiche technique
Fiche technique
IL-6 Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN6964085
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7092702
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123612
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL-6 Receptor
: "Endothelial HuR deletion reduces the expression of proatherogenic molecules and attenuates atherosclerosis." dans: International immunopharmacology, Vol. 65, pp. 248-255, (2018) (PubMed).: "The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma." dans: Gene, Vol. 585, Issue 1, pp. 51-7, (2016) (PubMed).
: "Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction." dans: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2015) (PubMed).
: "Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 33, Issue 10, pp. 1508-14, (2015) (PubMed).
: "Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor." dans: Acta pharmacologica Sinica, Vol. 35, Issue 11, pp. 1453-62, (2014) (PubMed).
: "Alterations of IL-6, IL-6R and gp130 in early and late onset severe preeclampsia." dans: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy, (2013) (PubMed).
: "Monoclonal anti-interleukin-6 receptor antibody attenuates donor-specific antibody responses in a mouse model of allosensitization." dans: Transplant immunology, Vol. 28, Issue 2-3, pp. 138-43, (2013) (PubMed).
: "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models." dans: Toxicology and applied pharmacology, Vol. 264, Issue 1, pp. 84-93, (2012) (PubMed).
: "Tumor necrosis factor-alpha (TNF-α)-blockade-induced hepatic sarcoidosis in psoriatic arthritis (PsA): case report and review of the literature." dans: Clinical rheumatology, Vol. 30, Issue 1, pp. 133-7, (2011) (PubMed).
: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." dans: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à IL-6 Receptor
interleukin 6 receptor (IL6R), interleukin 6 receptor (il6r), interleukin 6 receptor (Il6r), interleukin 6 receptor, alpha (Il6ra), CD126, gp80, IL-6R, IL-6R-1, il-6ra, IL-6RA, IL-6Ralpha, IL6Q, IL6R, Il6r, IL6R1, IL6RA, Il6ra, IL6RQProtein level used designations for IL-6 Receptor
- interleukin 6 receptor
- interleukin 6 receptor alpha
- interleukin-6 receptor subunit alpha
- CD126 antigen
- IL-6 receptor subunit alpha
- IL-6R 1
- membrane glycoprotein 80
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- interleukin 6 receptor, alpha
- IL-6 receptor alpha chain
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