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IL18BP Produits

(Interleukin 18 Binding Protein (IL18BP))
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].

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Catégories IL18BP en vedette

IL18BP Anticorps

High quality antibodies with extensive validation data.

IL18BP Kits ELISA

Reliable ELISA kits for a wide range of species.

IL18BP Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IL18BP recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7437905
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN6142329
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (1)
  • (1)
N° du produit ABIN752938
Quantité 100 μL
Fiche technique Fiche technique

IL18BP recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957071
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962912
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957070
Quantité 96 tests
Fiche technique Fiche technique

IL18BP recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7274976
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274973
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274977
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IL18BP

Zhang, Wang, Wang, Xie, Chen, He: "Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 354-373, (2019) (PubMed).

Wang, Liu, Wang, Wang, Chen, Xie, Zhang, He: "Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients." dans: Scandinavian journal of immunology, Vol. 87, Issue 5, pp. e12658, (2018) (PubMed).

Jurga, Piotrowska, Makuch, Przewlocka, Mika: "Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model." dans: Frontiers in pharmacology, Vol. 8, pp. 48, (2017) (PubMed).

Piotrowska, Popiolek-Barczyk, Pavone, Mika: "Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures." dans: Frontiers in cellular and infection microbiology, Vol. 7, pp. 141, (2017) (PubMed).

Businaro, Corsi, Azzara, Di Raimo, Laviola, Romano, Ricci, Maccarrone, Aronica, Fuso, Ricci: "Interleukin-18 modulation in autism spectrum disorders." dans: Journal of neuroinflammation, Vol. 13, pp. 2, (2016) (PubMed).

Hillestad, Espe, Cero, Larsen, Sjaastad, Nygård, Skjønsberg, Christensen: "IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice." dans: Acta physiologica (Oxford, England), Vol. 213, Issue 2, pp. 492-504, (2015) (PubMed).

Chen, Yuping, Ni: "Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction." dans: Molecular biology reports, Vol. 39, Issue 1, pp. 185-91, (2011) (PubMed).

He, Lu, Altmann, Hoke, Ljubanovic, Jani, Dinarello, Faubel, Edelstein: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." dans: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à IL18BP

interleukin 18 binding protein (IL18BP), interleukin 18 binding protein (Il18bp), Igifbp, IL-18BP, IL18BP, IL18BPa, MC54L

Protein level used designations for IL18BP

  • interleukin 18 binding protein
  • interferon gamma inducing factor binding protein
  • interferon gamma-inducing factor-binding protein
  • interleukin-18-binding protein
  • IL-18BP
  • MC51L-53L-54L homolog gene product
  • tadekinig-alfa
  • interleukin-18 binding protein
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