IL21 Receptor Produits
(Interleukin 21 Receptor (IL21R))
Catégories
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010].
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Catégories IL21 Receptor en vedette
IL21 Receptor Anticorps
High quality antibodies with extensive validation data.
IL21 Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
IL21 Receptor Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL21 Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN7193230
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7156852
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (1)
N° du produit
ABIN748148
Quantité
100 μL
Fiche technique
Fiche technique
IL21 Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957098
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN625319
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6384626
Quantité
96 tests
Fiche technique
Fiche technique
IL21 Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275021
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275014
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275007
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL21 Receptor
: "Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion." dans: BioMed research international, Vol. 2018, pp. 6728128, (2019) (PubMed).: "Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer." dans: Cells, Vol. 8, Issue 9, (2019) (PubMed).
: "IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 203, Issue 5, pp. 1142-1150, (2019) (PubMed).
: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." dans: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease." dans: Cytokine, Vol. 72, Issue 2, pp. 160-5, (2015) (PubMed).
: "IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5139-49, (2015) (PubMed).
: "CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3768-77, (2015) (PubMed).
: "Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity." dans: The Journal of experimental medicine, Vol. 209, Issue 3, pp. 581-96, (2012) (PubMed).
: "Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription." dans: Immunology, Vol. 132, Issue 4, pp. 540-8, (2011) (PubMed).
: "IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 9, pp. 5435-42, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à IL21 Receptor
interleukin 21 receptor (IL21R), interleukin 21 receptor, tandem duplicate 1 (il21r.1), interleukin 21 receptor (Il21r), CD360, il-21ra.a, IL21R, NILRProtein level used designations for IL21 Receptor
- interleukin-21 receptor
- interleukin 21 receptor
- interleukin 21 receptor alpha.a
- IL-21 receptor
- novel interleukin receptor
- IL-21R
- LR-beta
- NR8
- lymphocyte receptor beta
- novel cytokine receptor 8
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