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IL3RA Produits

(Interleukin 3 Receptor, alpha (IL3RA))

Catégories

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012].

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Catégories IL3RA en vedette

IL3RA Anticorps

High quality antibodies with extensive validation data.

IL3RA Kits ELISA

Reliable ELISA kits for a wide range of species.

IL3RA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IL3RA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application FACS, IHC, ELISA, ICC
Validations
  • (2)
  • (7)
N° du produit ABIN1724855
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (3)
  • (4)
N° du produit ABIN1176839
Quantité 100 tests
Fiche technique Fiche technique
Reactivity Human
Application IHC, ISt, StM
Validations
  • (5)
N° du produit ABIN6939783
Quantité 100 μg
Fiche technique Fiche technique

IL3RA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957129
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730726
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883419
Quantité 96 tests
Fiche technique Fiche technique

IL3RA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274943
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274946
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274938
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IL3RA

Baker, Nederveen, Parise: "Aerobic exercise in humans mobilizes HSCs in an intensity-dependent manner." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 122, Issue 1, pp. 182-190, (2017) (PubMed).

Drube, Weber, Loschinski, Beyer, Rothe, Rabenhorst, Göpfert, Meininger, Diamanti, Stegner, Häfner, Böttcher, Reinecke, Herdegen, Greten, Nieswandt, Hartmann, Krämer, Kamradt: "Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells." dans: Oncotarget, Vol. 6, Issue 7, pp. 5354-68, (2016) (PubMed).

Chung, Christopher-Stine, Paik, Corse, Mammen: "The composition of cellular infiltrates in anti-HMG-CoA reductase-associated myopathy." dans: Muscle & nerve, Vol. 52, Issue 2, pp. 189-95, (2015) (PubMed).

Leskela, Serrano, de la Fuente, Rodríguez-Muñoz, Ramos-Levi, Sampedro-Nuñez, Sánchez-Madrid, González-Amaro, Marazuela: "Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0123938, (2015) (PubMed).

Broughton, Hercus, Hardy, McClure, Nero, Dottore, Huynh, Braley, Barry, Kan, Dhagat, Scotney, Hartman, Busfield, Owczarek, Nash, Wilson, Parker, Lopez: "Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody." dans: Cell reports, Vol. 8, Issue 2, pp. 410-9, (2014) (PubMed).

Mirkina, Hadzijusufovic, Krepler, Mikula, Mechtcheriakova, Strommer, Stella, Jensen-Jarolim, Höller, Wacheck, Pehamberger, Valent: "Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R." dans: PLoS ONE, Vol. 9, Issue 1, pp. e84417, (2014) (PubMed).

Blatt, Herrmann, Hoermann, Willmann, Cerny-Reiterer, Sadovnik, Herndlhofer, Streubel, Rabitsch, Sperr, Mayerhofer, Rülicke, Valent: "Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 13, pp. 3589-602, (2014) (PubMed).

Koehl, Brehm, Huenecke, Zimmermann, Kloess, Bremm, Ullrich, Soerensen, Quaiser, Erben, Wunram, Gardlowski, Auth, Tonn, Seidl, Meyer-Monard, Stern, Passweg, Klingebiel, Bader, Schwabe, Esser: "Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol." dans: Frontiers in oncology, Vol. 3, pp. 118, (2013) (PubMed).

Salimi, Barlow, Saunders, Xue, Gutowska-Owsiak, Wang, Huang, Johnson, Scanlon, McKenzie, Fallon, Ogg: "A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis." dans: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2939-50, (2013) (PubMed).

Brehm, Huenecke, Quaiser, Esser, Bremm, Kloess, Soerensen, Kreyenberg, Seidl, Becker, Mühl, Klingebiel, Bader, Passweg, Schwabe, Koehl: "IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27351, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à IL3RA

interleukin 3 receptor subunit alpha (IL3RA), interleukin 3 receptor, alpha chain (Il3ra), interleukin 3 receptor subunit alpha (Il3ra), CD123, CDw123, Cyrl, hIL-3Ra, IL3R, IL3RAY, IL3RX, IL3RY, SUT-1

Protein level used designations for IL3RA

  • CD123 antigen
  • IL-3 receptor alpha SP2 isoform
  • IL-3 receptor subunit alpha
  • IL-3R subunit alpha
  • IL-3R-alpha
  • IL-3RA
  • interleukin-3 receptor subunit alpha
  • IL-3 receptor alpha chain
  • Il-3 alpha subunit
  • interleukin-3 receptor class II alpha chain
  • cytokine receptor-like protein CYRL
  • interleukin 3 receptor, alpha chain
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