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IL4 Receptor Produits

(Interleukin 4 Receptor (IL4R))

Catégories

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012].

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Catégories IL4 Receptor en vedette

IL4 Receptor Anticorps

High quality antibodies with extensive validation data.

IL4 Receptor Kits ELISA

Reliable ELISA kits for a wide range of species.

IL4 Receptor Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IL4 Receptor recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7434557
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7443335
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, FACS, ICC, IF (p), IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN740565
Quantité 100 μL
Fiche technique Fiche technique

IL4 Receptor recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
N° du produit ABIN6957153
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380459
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883422
Quantité 96 tests
Fiche technique Fiche technique

IL4 Receptor recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274993
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274989
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274992
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IL4 Receptor

Guimarães-Costa, Rochael, Oliveira, Echevarria-Lima, Saraiva: "Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages." dans: Frontiers in immunology, Vol. 8, pp. 523, (2017) (PubMed).

Nguyen, Frye, Zbesko, Stepanovic, Hayes, Urzua, Serrano, Beach, Doyle: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." dans: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).

Danelli, Frossi, Gri, Mion, Guarnotta, Bongiovanni, Tripodo, Mariuzzi, Marzinotto, Rigoni, Blank, Colombo, Pucillo: "Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." dans: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).

Mat?j, Sm?táková, Vašáková, Nováková, Sterclová, Kukal, Olejár: "PAR-2, IL-4R, TGF-? and TNF-? in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis." dans: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 533-538, (2014) (PubMed).

Biancheri, Di Sabatino, Ammoscato, Facciotti, Caprioli, Curciarello, Hoque, Ghanbari, Joe-Njoku, Giuffrida, Rovedatti, Geginat, Corazza, MacDonald: "Absence of a role for interleukin-13 in inflammatory bowel disease." dans: European journal of immunology, Vol. 44, Issue 2, pp. 370-85, (2014) (PubMed).

Reece, Gauvreau, Sehmi, Denburg: "IL-4 and IL-13 differentially regulate TLR-induced eosinophil-basophil differentiation of cord blood CD34+ progenitor cells." dans: PLoS ONE, Vol. 9, Issue 6, pp. e100734, (2014) (PubMed).

Sterclova, Matej, Mandakova, Skibova, Vasakova: "Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot study." dans: Multidisciplinary respiratory medicine, Vol. 8, Issue 1, pp. 35, (2013) (PubMed).

Vasakova, Sterclova, Stranska, Mandakova, Skibova, Matej: "Biomarkers of fibroproliferative healing in fibrosing idiopathic interstitial pneumonias." dans: The open respiratory medicine journal, Vol. 6, pp. 160-4, (2013) (PubMed).

Sarangthem, Cho, Bae, Singh, Kim, Kim, Jeon, Lee, Park: "Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide." dans: PLoS ONE, Vol. 8, Issue 12, pp. e81891, (2013) (PubMed).

Boulaftali, Hess, Getz, Cholka, Stolla, Mackman, Owens, Ware, Kahn, Bergmeier: "Platelet ITAM signaling is critical for vascular integrity in inflammation." dans: The Journal of clinical investigation, Vol. 123, Issue 2, pp. 908-16, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à IL4 Receptor

interleukin 4 receptor (IL4R), interleukin 4 receptor, tandem duplicate 1 (il4r.1), interleukin 4 receptor (Il4r), interleukin 4 receptor, alpha (Il4ra), CD124, il-4ra, IL-4RA, IL4, IL4R, Il4r, IL4RA, Il4ra, zgc:113063

Protein level used designations for IL4 Receptor

  • interleukin 4 receptor alpha chain
  • interleukin-4 receptor alpha chain
  • interleukin-4 receptor subunit alpha
  • interleukin 4 receptor
  • IL-4RA-like protein 1
  • il-4alpha
  • interleukin 4 receptor alpha
  • soluble IL-4 receptor alpha
  • interleukin-4 receptor subunit alpha-like
  • IL-4 receptor subunit alpha
  • IL4R nirs variant 1
  • IL-4R subunit alpha
  • IL-4R-alpha
  • IL-4RA
  • interleukin 4 receptor, alpha
  • interleukin 4 tv3
  • interleukin 4 tv5
  • interleukin-4 receptor alpha-chain
  • IL-4 receptor alpha chain
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