IL5RA Produits
(Interleukin 5 Receptor, alpha (IL5RA))
Catégories
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011].
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Catégories IL5RA en vedette
IL5RA Anticorps
High quality antibodies with extensive validation data.
IL5RA Kits ELISA
Reliable ELISA kits for a wide range of species.
IL5RA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL5RA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7433729
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN7193317
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7433726
Quantité
100 μL
Fiche technique
Fiche technique
IL5RA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957164
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957165
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730708
Quantité
96 tests
Fiche technique
Fiche technique
IL5RA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275035
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275042
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275023
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL5RA
: "Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltration in the lung." dans: International immunopharmacology, Vol. 43, pp. 140-146, (2016) (PubMed).: "Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling." dans: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40091-103, (2011) (PubMed).
: "Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties." dans: Journal of leukocyte biology, Vol. 89, Issue 2, pp. 311-7, (2011) (PubMed).
: "Separate endocytic pathways regulate IL-5 receptor internalization and signaling." dans: Journal of leukocyte biology, Vol. 84, Issue 2, pp. 499-509, (2008) (PubMed).
: "Identification of UNC119 as a novel activator of SRC-type tyrosine kinases." dans: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8837-45, (2003) (PubMed).
: "T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta." dans: The Journal of allergy and clinical immunology, Vol. 110, Issue 4, pp. 624-33, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à IL5RA
interleukin 5 receptor subunit alpha L homeolog (il5ra.L), interleukin 5 receptor subunit alpha (IL5RA), interleukin 5 receptor subunit alpha (il5ra), interleukin 5 receptor subunit alpha (Il5ra), interleukin 5 receptor, alpha (Il5ra), CD125, cdw125, CDw125, gpIL-5ra, hsil5r3, HSIL5R3, il5r, IL5R, Il5r, IL5RA, MGC86517Protein level used designations for IL5RA
- interleukin 5 receptor, alpha
- Interleukin-5 receptor subunit alpha
- interleukin-5 receptor subunit alpha
- interleukin 5 receptor alpha
- interleukin-5 receptor, alpha
- interleukin-5 receptor subunit alpha-like
- CD125 antigen
- IL-5 receptor subunit alpha
- IL-5R subunit alpha
- interleukin 5 receptor type 3
- interleukin-5 receptor alpha chain
- IL-5 receptor alpha chain
- IL-5R-alpha
- IL-5RA
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