IL6RA Produits
(Interleukin 6 Receptor, alpha (IL6RA))
Catégories
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
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Catégories IL6RA en vedette
IL6RA Anticorps
High quality antibodies with extensive validation data.
IL6RA Kits ELISA
Reliable ELISA kits for a wide range of species.
IL6RA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL6RA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
Validations
- (2)
- (2)
N° du produit
ABIN734693
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
N° du produit
ABIN3181401
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC (fro), IHC (p)
Validations
N° du produit
ABIN734695
Quantité
100 μL
Fiche technique
Fiche technique
IL6RA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968019
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6719752
Quantité
1 kit
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1138704
Quantité
96 tests
Fiche technique
Fiche technique
IL6RA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275036
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275037
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275024
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL6RA
: "STAT-3-independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection." dans: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1079-1090, (2019) (PubMed).: "Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner." dans: Immunity, inflammation and disease, Vol. 4, Issue 4, pp. 413-426, (2018) (PubMed).
: "Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells." dans: Arthritis research & therapy, Vol. 19, Issue 1, pp. 137, (2017) (PubMed).
: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." dans: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).
: "Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling." dans: Scientific reports, Vol. 7, pp. 44053, (2017) (PubMed).
: "Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130." dans: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 121, (2017) (PubMed).
: "IL-6 trans-signaling is another pathway to upregulate Osteopontin." dans: Cytokine, Vol. 90, pp. 88-95, (2016) (PubMed).
: "Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium." dans: PLoS ONE, Vol. 11, Issue 5, pp. e0155161, (2016) (PubMed).
: "Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0130395, (2015) (PubMed).
: "Easy and rapid binding assay for functional analysis of disulfide-containing peptides by a pull-down method using a puromycin-linker and a cell-free translation system." dans: Biology, Vol. 4, Issue 1, pp. 161-72, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à IL6RA
interleukin 6 receptor (Il6r), interleukin 6 receptor (IL6R), interleukin 6 receptor, alpha (Il6ra), CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL6Q, Il6r, IL6R1, Il6ra, IL6RA, IL6RQProtein level used designations for IL6RA
- IL-6 receptor subunit alpha
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- interleukin 6 receptor, alpha
- interleukin-6 receptor subunit alpha
- CD126 antigen
- membrane glycoprotein 80
- IL-6 receptor alpha chain
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