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IMPDH2 Produits

(IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Catégories

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008].

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Catégories IMPDH2 en vedette

IMPDH2 Anticorps

High quality antibodies with extensive validation data.

IMPDH2 Kits ELISA

Reliable ELISA kits for a wide range of species.

IMPDH2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IMPDH2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP, RNAi
Validations
  • (1)
  • (4)
N° du produit ABIN561488
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7156292
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (4)
N° du produit ABIN2855167
Quantité 100 μL
Fiche technique Fiche technique

IMPDH2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967575
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967574
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956714
Quantité 96 tests
Fiche technique Fiche technique

IMPDH2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307895
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123412
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408207
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IMPDH2

Barfeld, Fazli, Persson, Marjavaara, Urbanucci, Kaukoniemi, Rennie, Ceder, Chabes, Visakorpi, Mills: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." dans: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).

Li, Meng, Liu, Li, Zhang, Bao, Song, Li: "IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells." dans: European review for medical and pharmacological sciences, Vol. 18, Issue 20, pp. 3038-44, (2014) (PubMed).

Wawrzyniak, Bianchi-Smiraglia, Bshara, Mannava, Ackroyd, Bagati, Omilian, Im, Fedtsova, Miecznikowski, Moparthy, Zucker, Zhu, Kozlova, Berman, Hoek, Gudkov, Shewach, Morrison, Nikiforov: "A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion." dans: Cell reports, Vol. 5, Issue 2, pp. 493-507, (2013) (PubMed).

Nogueira da Costa, Mijal, Keen, Findlay, Wild: "Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol." dans: Proteomics, Vol. 11, Issue 10, pp. 1903-14, (2011) (PubMed).

Floryk, Thompson: "Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells." dans: International journal of cancer, Vol. 123, Issue 10, pp. 2294-302, (2008) (PubMed).

Mannava, Grachtchouk, Wheeler, Im, Zhuang, Slavina, Mathews, Shewach, Nikiforov: "Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells." dans: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 15, pp. 2392-400, (2008) (PubMed).

Fellenberg, Bernd, Delling, Witte, Zahlten-Hinguranage: "Prognostic significance of drug-regulated genes in high-grade osteosarcoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 10, pp. 1085-94, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à IMPDH2

inosine monophosphate dehydrogenase 2 (IMPDH2), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2.S), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (Impdh2), inosine 5'-phosphate dehydrogenase 2 (impdh2), cb635, imp2, IMPD, impd2, IMPD2, IMPD 2, impdh-ii, IMPDH-II, impdh2, IMPDH 2, wu:fb64g02, wu:fc43f09

Protein level used designations for IMPDH2

  • IMP (inosine monophosphate) dehydrogenase 2
  • inosine monophosphate dehydrogenase 2
  • IMP (inosine 5'-monophosphate) dehydrogenase 2
  • hCG2002013-like
  • inosine-5'-monophosphate dehydrogenase 2-like
  • IMP oxireductase 2
  • IMPD 2
  • IMPDH 2
  • inosine 5' phosphate dehydrogenase 2
  • inosine monophosphate dehydrogenase type II
  • inosine-5'-monophosphate dehydrogenase 2
  • IMP dehydrogenase 2
  • IMPDH-II
  • inosine 5'-phosphate dehydrogenase 2
  • inosine 5-monophosphate dehydrogenase 2
  • IMP dehydrogenase type II
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