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Inner Centromere Protein Antigens 135/155kDa Produits

(Inner Centromere Protein Antigens 135/155kDa (INCENP))
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A\; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143)\; MCAK (MIM 604538)\; KID (MIM 603213)\; cytoplasmic dynein (e.g., MIM 600112)\; CliPs (e.g., MIM 179838)\; and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008].

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Catégories Inner Centromere Protein Antigens 135/155kDa en vedette

Inner Centromere Protein Antigens 135/155kDa Anticorps

High quality antibodies with extensive validation data.

Inner Centromere Protein Antigens 135/155kDa Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Inner Centromere Protein Antigens 135/155kDa recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application FACS, ELISA, ICC, IHC
Validations
  • (2)
  • (7)
N° du produit ABIN969529
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, FACS, ELISA, IHC
Validations
  • (7)
N° du produit ABIN1491465
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, ELISA, IHC, IF/ICC
Validations
  • (8)
N° du produit ABIN1844019
Quantité 100 μL
Fiche technique Fiche technique

Inner Centromere Protein Antigens 135/155kDa recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
N° du produit ABIN6699954
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Inner Centromere Protein Antigens 135/155kDa

Ban, Nishida, Urano: "Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 6, pp. 652-69, (2011) (PubMed).

Wang, Ballister, Lampson: "Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient." dans: The Journal of cell biology, Vol. 194, Issue 4, pp. 539-49, (2011) (PubMed).

Xu, Ogawa, Vagnarelli, Bergmann, Hudson, Ruchaud, Fukagawa, Earnshaw, Samejima: "INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization." dans: The Journal of cell biology, Vol. 187, Issue 5, pp. 637-53, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à Inner Centromere Protein Antigens 135/155kDa

inner centromere protein (INCENP), inner centromere protein (Incenp), inner centromere protein S homeolog (incenp.S), inner centromere protein (incenp), inner centromere protein L homeolog (incenp.L), 2700067E22Rik, AU019509, C77457, C130081E20, INCENP, incenp, incenp-a, incenp-b, LOC572121, xINC, xIncenp, XL-INCENP, xl-incenp

Protein level used designations for Inner Centromere Protein Antigens 135/155kDa

  • binds and activates aurora-B and -C in vivo and in vitro
  • chromosomal passenger protein
  • inner centromere protein
  • inner centromere protein INCENP
  • inner centromere protein antigens 135/155kDa
  • class I INCENP protein
  • class II INCENP protein
  • inner centromere protein B
  • similar to XL-INCENP
  • inner centromere protein-like
  • Mitotic phosphoprotein 130
  • inner centromere protein A
  • mitotic phosphoprotein 130
  • xINC
  • xIncenp
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