Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

INPP5D Produits

(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories INPP5D en vedette

INPP5D Anticorps

High quality antibodies with extensive validation data.

INPP5D Kits ELISA

Reliable ELISA kits for a wide range of species.

INPP5D Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

INPP5D recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
anti-INPP5D anticorps (AA 959-1188)
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6213625
Quantité 100 μL
Fiche technique Fiche technique
Recombinant anti-INPP5D anticorps
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (3)
N° du produit ABIN7127806
Quantité 100 μL
Fiche technique Fiche technique
anti-INPP5D anticorps (C-Term)
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
N° du produit ABIN6265066
Quantité 100 μL
Fiche technique Fiche technique

INPP5D recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
INPP5D Kit ELISA
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN4889790
Quantité 96 tests
Fiche technique Fiche technique
INPP5D Kit ELISA
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956751
Quantité 96 tests
Fiche technique Fiche technique
INPP5D Kit ELISA
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (2)
N° du produit ABIN4889791
Quantité 96 tests
Fiche technique Fiche technique

INPP5D recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
INPP5D Protein (AA 1-1189) (Strep Tag)
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095410
Quantité 1 mg
Fiche technique Fiche technique
INPP5D Protein (AA 1-1191) (Strep Tag)
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3137223
Quantité 1 mg
Fiche technique Fiche technique
INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2723485
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits INPP5D

Tu, Liu, Dong, Yu, Wang, Chen: "Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1: a meaningful and independent marker to predict stroke in the Chinese population." dans: Journal of molecular neuroscience : MN, Vol. 52, Issue 4, pp. 507-14, (2014) (PubMed).

Sácha, Zámecník, Barinka, Hlouchová, Vícha, Mlcochová, Hilgert, Eckschlager, Konvalinka: "Expression of glutamate carboxypeptidase II in human brain." dans: Neuroscience, Vol. 144, Issue 4, pp. 1361-72, (2007) (PubMed).

Rovenská, Hlouchová, Sácha, Mlcochová, Horák, Zámecník, Barinka, Konvalinka: "Tissue expression and enzymologic characterization of human prostate specific membrane antigen and its rat and pig orthologs." dans: The Prostate, Vol. 68, Issue 2, pp. 171-82, (2007) (PubMed).

Mesters, Barinka, Li, Tsukamoto, Majer, Slusher, Konvalinka, Hilgenfeld: "Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer." dans: The EMBO journal, Vol. 25, Issue 6, pp. 1375-84, (2006) (PubMed).

Rotblat, Yizhar, Haklai, Ashery, Kloog: "Ras and its signals diffuse through the cell on randomly moving nanoparticles." dans: Cancer research, Vol. 66, Issue 4, pp. 1974-81, (2006) (PubMed).

Roy, Plowman, Rotblat, Prior, Muncke, Grainger, Parton, Henis, Kloog, Hancock: "Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling." dans: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6722-33, (2005) (PubMed).

Maxwell, Yuan, Anderson, Hibbs, Salem, Jackson: "SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets." dans: The Journal of biological chemistry, Vol. 279, Issue 31, pp. 32196-204, (2004) (PubMed).

Rotblat, Prior, Muncke, Parton, Kloog, Henis, Hancock: "Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane." dans: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6799-810, (2004) (PubMed).

Giuriato, Pesesse, Bodin, Sasaki, Viala, Marion, Penninger, Schurmans, Erneux, Payrastre: "SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels." dans: The Biochemical journal, Vol. 376, Issue Pt 1, pp. 199-207, (2003) (PubMed).

Jiang, Stuible, Chalandon, Li, Chan, Eisterer, Krystal, Eaves, Eaves: "Evidence for a positive role of SHIP in the BCR-ABL-mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia." dans: Blood, Vol. 102, Issue 8, pp. 2976-84, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à INPP5D

inositol polyphosphate-5-phosphatase D (INPP5D), phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045), inositol polyphosphate-5-phosphatase D (inpp5d), inositol polyphosphate 5-phosphatase (EHI_159880), inositol polyphosphate 5-phosphatase (EHI_153490), inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L), phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693), inositol polyphosphate-5-phosphatase D (Inpp5d), 13.t00027, 256.t00004, AI323613, hp51CN, INPP5D, s-SHIP, ship, SHIP, SHIP-1, ship1, SHIP1, SIP-145

Protein level used designations for INPP5D

  • inositol polyphosphate-5-phosphatase, 145kDa
  • SH2 containing inositol phosphatase
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like
  • SH2 domain-containing inositol 5'-phosphatase 1
  • SH2 domain-containing inositol phosphatase 1
  • SH2 domain-containing inositol-5'-phosphatase 1
  • SHIP-1
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
  • Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
  • SH2 containing inositol phosphotase
  • SH2-containing inositol phosphatase SHIP
  • SIP-145
  • Src homology 2 domain-containing inositol-5-phosphatase
  • inositol polyphosphate-5-phosphatase of 145 kDa
  • inositol polyphosphate-5-phosphatase, 145 kDa
  • p150Ship
  • Inositol polyphosphate-5-phosphatase 145 kDa
  • Inositol polyphosphate-5-phosphatase, 145 kDa
  • signaling inositol polyphosphate 5 phosphatase SIP-145

Avez-vous cherché autre chose?

Vous êtes ici:

antibodies-online

allemand

german (deutsch) antikoerper-online.de

Anglais

english (english) antibodies-online.com

français

french (français) anticorps-enligne.fr

chinois

chinese (中文) antibodies-online.cn

genomics-online

Anglais

english (english) genomics-online.com

Support technique