Dabigatran etexilate
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- Application
- Inhibition Assay (InhA), Functional Studies (Func)
- Fonction
- Dabigatran etexilate is an oral prodrug that is metabolized by a serum esterase to dabigatran. It is a synthetic, competitive and reversible direct thrombin inhibitor. Inhibition of thrombin disrupts the coagulation cascade and inhibits the formation of clots. Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients who have undergone total hip or knee replacement surgery, or to prevent stroke and systemic embolism in patients with atrial fibrillation, in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary. FDA approved on October 19, 2010.
- Attributs du produit
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Tradename: PRADAXA
Source of Compound: synthetic, BIBR-1048
Target: Thrombin inhibitor
Receptor: Thrombin
- Purification
- All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
- Pureté
- 98 %
- Formula
- C34H41N7O5
- Solubility
- Soluble in water
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Stock
- -20 °C
- Stockage commentaire
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For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. - Date de péremption
- 24 months
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- Sujet
- Angiogenesis
- Poids moléculaire
- 627.73 g/mol
- Numéro CAS
- 211915-06-9
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