AG-490 (Tyrphostin B42)
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- Application
- Inhibition Assay (InhA), Functional Studies (Func)
- Fonction
- AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR with IC50 of 0.1 μM, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.
- Attributs du produit
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Target: EGFR inhibitor, JAK inhibitor, HER2 inhibitor
Receptor: EGFR,JAK2,ErbB2 - Purification
- All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
- Pureté
- 98.80 %
- Formula
- C17H14N2O3
- Solubility
- 100 mM in DMSO
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Stock
- -20 °C
- Stockage commentaire
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For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. - Date de péremption
- 24 months
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- Sujet
- JAK/STAT Signaling,Tyrosine Kinase/Adaptors
- Poids moléculaire
- 294.30 g/mol
- Numéro CAS
- 133550-30-8
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